Cell Biology Antibodies 14

Anti-FOXG1 Antibody (CAB16851)

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SKU:
CAB16851
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-FOXG1 Antibody
Antibody SKU:CAB16851
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide of human FOXG1.
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:U-251MG, SH-SY5Y, 293T, mouse brain, mouse kidney, mouse spleen, rat brain, rat kidney, rat spleen
Immunogen:A synthetic peptide of human FOXG1.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:2290
Uniprot:P55316
Cellular Location:
Calculated MW:52kDa
Observed MW:52kDa
Anti-FOXG1 Antibody (CAB16851)Western blot - FOXG1 Polyclonal Antibody (CAB16851)
Synonyms:FOXG1, BF1, BF2, FHKL3, FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1A, FOXG1B, FOXG1C, HBF-1, HBF-2, HBF-3, HBF-G2, HBF2, HFK1, HFK2, HFK3, KHL2, QIN
Background:This locus encodes a member of the forked-head transcription factor family. The encoded protein, which functions as a repressor, may play a role in brain development. Mutations at this locus have been associated with Rett syndrome.
UniProt Protein Function:FOXG1: Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon. Interacts with KDM5B. Expression is restricted to the neurons of the developing telencephalon.
UniProt Protein Details:

Protein type:DNA-binding; Transcription factor; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 14q13

Cellular Component: nucleus

Molecular Function:protein binding; DNA binding; sequence-specific DNA binding; transcription factor activity

Biological Process: transcription, DNA-dependent; brain development; negative regulation of transcription, DNA-dependent; aging

Disease: Rett Syndrome, Congenital Variant

NCBI Summary:This locus encodes a member of the forked-head transcription factor family. The encoded protein, which functions as a repressor, may play a role in brain development. Mutations at this locus have been associated with Rett syndrome. [provided by RefSeq, Feb 2012]
UniProt Code:P55316
NCBI GenInfo Identifier:152031604
NCBI Gene ID:2290
NCBI Accession:P55316.2
UniProt Secondary Accession:P55316,Q60987, Q00939,
UniProt Related Accession:P55316
Molecular Weight:489
NCBI Full Name:Forkhead box protein G1
NCBI Synonym Full Names:forkhead box G1
NCBI Official Symbol:FOXG1  
NCBI Official Synonym Symbols:BF1; BF2; QIN; FKH2; HBF2; HFK1; HFK2; HFK3; KHL2; FHKL3; FKHL1; FKHL2; FKHL3; FKHL4; HBF-1; HBF-2; HBF-3; FOXG1A; FOXG1B; FOXG1C; HBF-G2  
NCBI Protein Information:forkhead box protein G1; oncogene QIN; brain factor 1; brain factor 2; forkhead-like 1; forkhead-like 2; forkhead-like 3; forkhead-like 4
UniProt Protein Name:Forkhead box protein G1
UniProt Synonym Protein Names:Brain factor 1; BF-1; BF1; Brain factor 2; BF-2; BF2; hBF-2; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; Forkhead-related protein FKHL1; HFK1; Forkhead-related protein FKHL2; HFK2; Forkhead-related protein FKHL3; HFK3
UniProt Gene Name:FOXG1  
UniProt Entry Name:FOXG1_HUMAN
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