Cell Biology Antibodies 6
Anti-FNTB Antibody (CAB15671)
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- SKU:
- CAB15671
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-FNTB Antibody |
| Antibody SKU: | CAB15671 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human FNTB (NP_002019.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, HeLa, HepG2, K-562, Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human FNTB (NP_002019.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MASP SSFT YYCP PSSS PVWS EPLY SLRP EHAR ERLQ DDSV ETVT SIEQ AKVE EKIQ EVFS SYKF NHLV PRLV LQRE KHFH YLKR GLRQ LTDA YECL DASR PWLC YWIL HSLE LLDE PIPQ |
| Gene ID: | 2342 |
| Uniprot: | P49356 |
| Cellular Location: | |
| Calculated MW: | 43kDa/48kDa |
| Observed MW: | 49kDa |
| Synonyms: | FNTB, FPTB, farnesyltransferase, CAAX box, beta |
| Background: |
| UniProt Protein Function: | FNTB: a subunit of farnesyltransferase that is responsible for peptide-binding. Farnesyltransferase catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. |
| UniProt Protein Details: | Protein type:Transferase; EC 2.5.1.58 Chromosomal Location of Human Ortholog: 14q23.3 Cellular Component: cytosol; microtubule associated complex Molecular Function:protein binding; protein farnesyltransferase activity; zinc ion binding Biological Process: protein farnesylation; regulation of rhodopsin mediated signaling |
| NCBI Summary: | This locus represents naturally occurring read-through transcription between the neighboring CHURC1 (churchill domain containing 1) and FNTB (farnesyltransferase, CAAX box, beta) on chromosome 14. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Feb 2011] |
| UniProt Code: | P49356 |
| NCBI GenInfo Identifier: | 1346696 |
| NCBI Gene ID: | 100529261 |
| NCBI Accession: | P49356.1 |
| UniProt Secondary Accession: | P49356,B2RDX6, B4E1A0, |
| Molecular Weight: | 43,574 Da |
| NCBI Full Name: | Protein farnesyltransferase subunit beta |
| NCBI Synonym Full Names: | CHURC1-FNTB readthrough |
| NCBI Official Symbol: | CHURC1-FNTB |
| NCBI Protein Information: | CHURC1-FNTB protein |
| UniProt Protein Name: | Protein farnesyltransferase subunit beta |
| UniProt Synonym Protein Names: | CAAX farnesyltransferase subunit beta; Ras proteins prenyltransferase subunit beta |
| UniProt Gene Name: | FNTB |
| UniProt Entry Name: | FNTB_HUMAN |
 | Western blot analysis of extracts of various cell lines, using FNTB antibody (CAB15671) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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