Cell Biology Antibodies 9
Anti-FKBPL Antibody (CAB4916)
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- SKU:
- CAB4916
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- FKBPL
- Synonyms:
- DIR1
- Synonyms:
- FKBP4
- Synonyms:
- NG7
- Synonyms:
- WISP39
- Research Area:
- Cell Biology
Description
| Product Name: | FKBPL Rabbit pAb |
| Product Code: | CAB4916 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | FKBPL, DIR1, FKBP4, NG7, WISP39 |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-349 of human FKBPL (NP_071393.2). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:200 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | 22Rv1, A-549, SKOV3, MCF7 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-349 of human FKBPL (NP_071393.2). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | METP PVNT IGEK DTSQ PQQE WEKN LREN LDSV IQIR QQPR DPPT ETLE LEVS PDPA SQIL EHTQ GAEK LVAE LEGD SHKS HGST SQMP EALQ ASDL WYCP DGSF VKKI VIRG HGLD KPKL GSCC RVLA LGFP FGSG PPEG WTEL TMGV GPWR EETW GELI EKCL ESMC QGEE AELQ LPGH SGPP VRLT LASF TQGR DSWE LETS EKEA LARE ERAR GTEL FRAG NPEG AARC YGRA LRLL LTLP PPGP PERT VLHA NLAA CQLL LGQP QLAA QSCD RVLE REPG HLKA LYRR GVAQ AALG NLEK ATAD LKKV LAID PKNR AAQE ELGK VVIQ GKNQ DAGL AQGL RKMF G |
| Gene ID: | 63943 |
| Uniprot: | Q9UIM3 |
| Calculated MW: | 38kDa |
| Observed MW: | 45kDa |
| UniProt Protein Function: | FKBPL: May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: cytosol; endoplasmic reticulum membrane Molecular Function:FK506 binding; peptidyl-prolyl cis-trans isomerase activity; protein binding Biological Process: protein stabilization |
| NCBI Summary: | The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UIM3 |
| NCBI GenInfo Identifier: | 74762773 |
| NCBI Gene ID: | 63943 |
| NCBI Accession: | Q9UIM3.1 |
| UniProt Secondary Accession: | Q9UIM3,Q9H5G3, A8K5V3, B0UYX8, |
| UniProt Related Accession: | Q9UIM3 |
| Molecular Weight: | 38,176 Da |
| NCBI Full Name: | FK506-binding protein-like |
| NCBI Synonym Full Names: | FK506 binding protein like |
| NCBI Official Symbol: | FKBPL |
| NCBI Official Synonym Symbols: | NG7; DIR1; FKBP4; WISP39 |
| NCBI Protein Information: | FK506-binding protein-like |
| UniProt Protein Name: | FK506-binding protein-like |
| UniProt Synonym Protein Names: | WAF-1/CIP1 stabilizing protein 39; WISp39 |
| Protein Family: | FK506-binding protein |
| UniProt Gene Name: | FKBPL |
| UniProt Entry Name: | FKBPL_HUMAN |
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