Cardiovascular Antibodies

Anti-FILIP1L Antibody (CAB17861)

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SKU:
CAB17861
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cardiovascular

Description

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Antibody Name:Anti-FILIP1L Antibody
Antibody SKU:CAB17861
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FILIP1L (NP_878913.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:HT-29, mouse ovary, A375
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FILIP1L (NP_878913.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MRSR GSDT EGSA QKKF PRHT KGHS FQGP KNMK HRQQ DKDS PSES DVIL PCPK AEKP HSGN GHQA EDLS RDDL LFLL SILE GELQ ARDE VIGI LKAE KMDL ALLE AQYG FVTP KKVL EALQ RDAF QAKS TPWQ EDIY EKPM NELD KVVE KHKE SYRR ILGQ LLVA EKSR RQTI LELE EEKR KHKE YMEK SDEF ICLL EQEC
Gene ID:11259
Uniprot:Q4L180
Cellular Location:
Calculated MW:130kDa
Observed MW:110kDa
Synonyms:DOC1, DOC-1, GIP90, GIP130, FILIP1L
Background:
UniProt Protein Function:FILIP1L: Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor- associated vasculature. Belongs to the FILIP1 family. 7 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: 3q12.1

UniProt Code:Q4L180
NCBI GenInfo Identifier:162416295
NCBI Gene ID:11259
NCBI Accession:Q4L180.2
UniProt Secondary Accession:Q4L180,Q13597, Q2YDY5, Q6KFX5, Q6KFX6, Q6KFX7, Q8IUM3 Q8N6Z0, B2CNV7, B2CNV8,
UniProt Related Accession:Q4L180
Molecular Weight:102,441 Da
NCBI Full Name:Filamin A-interacting protein 1-like
NCBI Synonym Full Names:filamin A interacting protein 1 like
NCBI Official Symbol:FILIP1L  
NCBI Official Synonym Symbols:DOC1; DOC-1; GIP90; GIP130  
NCBI Protein Information:filamin A-interacting protein 1-like
UniProt Protein Name:Filamin A-interacting protein 1-like
UniProt Synonym Protein Names:130 kDa GPBP-interacting protein; 90 kDa GPBP-interacting protein; Protein down-regulated in ovarian cancer 1; DOC-1
Protein Family:Filamin A-interacting protein
UniProt Gene Name:FILIP1L  
UniProt Entry Name:FIL1L_HUMAN
Anti-FILIP1L Antibody (CAB17861)Western blot analysis of extracts of various cell lines, using FILIP1L antibody (CAB17861) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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