Cell Biology Antibodies 4
Anti-FGL2 Antibody (CAB13755)
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- SKU:
- CAB13755
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-FGL2 Antibody |
| Antibody SKU: | CAB13755 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-140 of human FGL2 (NP_006673.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-140 of human FGL2 (NP_006673.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | NNET EEIK DERA KDVC PVRL ESRG KCEE AGEC PYQV SLPP LTIQ LPKQ FSRI EEVF KEVQ NLKE IVNS LKKS CQDC KLQA DDNG DPGR NGLL LPST GAPG EVGD NRVR ELES EVNK L |
| Gene ID: | 10875 |
| Uniprot: | Q14314 |
| Cellular Location: | Secreted |
| Calculated MW: | 50kDa |
| Observed MW: | 70kDa |
| Synonyms: | FGL2, T49, pT49 |
| Background: | The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites. |
| UniProt Protein Function: | FGL2: May play a role in physiologic lymphocyte functions at mucosal sites. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 7q11.23 Cellular Component: fibrinogen complex |
| NCBI Summary: | The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q14314 |
| NCBI GenInfo Identifier: | 12230074 |
| NCBI Gene ID: | 10875 |
| NCBI Accession: | Q14314.1 |
| UniProt Related Accession: | Q14314 |
| Molecular Weight: | |
| NCBI Full Name: | Fibroleukin |
| NCBI Synonym Full Names: | fibrinogen like 2 |
| NCBI Official Symbol: | FGL2 |
| NCBI Official Synonym Symbols: | T49; pT49 |
| NCBI Protein Information: | fibroleukin |
| UniProt Protein Name: | Fibroleukin |
| UniProt Synonym Protein Names: | Fibrinogen-like protein 2; pT49 |
| Protein Family: | Fibroleukin |
| UniProt Gene Name: | FGL2 |
| UniProt Entry Name: | FGL2_HUMAN |
 | Western blot analysis of extracts of HepG2 cells, using FGL2 antibody (CAB13755) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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