Immunology Antibodies 2
Anti-FGL1 Antibody (CAB3862)
- SKU:
- CAB3862
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-FGL1 Antibody |
| Antibody SKU: | CAB3862 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-312 of human FGL1 (NP_004458.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:1000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-312 of human FGL1 (NP_004458.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAKV FSFI LVTT ALTM GREI SALE DCAQ EQMR LRAQ VRLL ETRV KQQQ VKIK QLLQ ENEV QFLD KGDE NTVI DLGS KRQY ADCS EIFN DGYK LSGF YKIK PLQS PAEF SVYC DMSD GGGW TVIQ RRSD GSEN FNRG WKDY ENGF GNFV QKHG EYWL GNKN LHFL TTQE DYTL KIDL ADFE KNSR YAQY KNFK VGDE KNFY ELNI GEYS GTAG DSLA GNFH PEVQ WWAS HQRM KFST WDRD HDNY EGNC AEED QSGW WFNR CHSA NLNG VYYS GPYT AKTD NGIV WYTW HGWW YSLK SVVM KIRP NDFI PNVI |
| Gene ID: | 2267 |
| Uniprot: | Q08830 |
| Cellular Location: | Secreted |
| Calculated MW: | 36kDa |
| Observed MW: | Refer to figures |
| Synonyms: | FGL1, HFREP1, HP-041, LFIRE-1, LFIRE1 |
| Background: | Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. |
| UniProt Protein Function: | FGL1: Has hepatocyte mitogenic activity. |
| UniProt Protein Details: | Protein type:Extracellular matrix; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 8p22 Cellular Component: fibrinogen complex Biological Process: cholesterol metabolic process |
| NCBI Summary: | Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q08830 |
| NCBI GenInfo Identifier: | 147744562 |
| NCBI Gene ID: | 2267 |
| NCBI Accession: | Q08830.3 |
| UniProt Secondary Accession: | Q08830,Q4PJH9, Q53YF1, Q8NG32, Q96KW6, Q96QM6, A6NKU4 |
| UniProt Related Accession: | Q08830 |
| Molecular Weight: | 312 |
| NCBI Full Name: | Fibrinogen-like protein 1 |
| NCBI Synonym Full Names: | fibrinogen-like 1 |
| NCBI Official Symbol: | FGL1 |
| NCBI Official Synonym Symbols: | HFREP1; HP-041; LFIRE1; LFIRE-1 |
| NCBI Protein Information: | fibrinogen-like protein 1; hepassocin; liver fibrinogen-related protein 1; hepatocellular carcinoma-related sequence; hepatocyte-derived fibrinogen-related protein 1 |
| UniProt Protein Name: | Fibrinogen-like protein 1 |
| UniProt Synonym Protein Names: | HP-041; Hepassocin; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; Liver fibrinogen-related protein 1; LFIRE-1 |
| Protein Family: | Fibrinogen-like protein |
| UniProt Gene Name: | FGL1 |
| UniProt Entry Name: | FGL1_HUMAN |
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