Immunology Antibodies 1
Anti-FGL1 Antibody (CAB10977)
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- SKU:
- CAB10977
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-FGL1 Antibody |
| Antibody SKU: | CAB10977 |
| Antibody Size: | 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic Peptide of human FGL1 |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | fetal liver |
| Immunogen: | A synthetic Peptide of human FGL1 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2267 |
| Uniprot: | Q08830 |
| Cellular Location: | Secreted |
| Calculated MW: | 36kDa |
| Observed MW: | 36kDa |
| Synonyms: | FGL1, HFREP1, HP-041, LFIRE-1, LFIRE1 |
| Background: | Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. |
| UniProt Protein Function: | FGL1: Has hepatocyte mitogenic activity. |
| UniProt Protein Details: | Protein type:Extracellular matrix; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 8p22 Cellular Component: fibrinogen complex Biological Process: cholesterol metabolic process |
| NCBI Summary: | Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q08830 |
| NCBI GenInfo Identifier: | 147744562 |
| NCBI Gene ID: | 2267 |
| NCBI Accession: | Q08830.3 |
| UniProt Secondary Accession: | Q08830,Q4PJH9, Q53YF1, Q8NG32, Q96KW6, Q96QM6, A6NKU4 |
| UniProt Related Accession: | Q08830 |
| Molecular Weight: | 312 |
| NCBI Full Name: | Fibrinogen-like protein 1 |
| NCBI Synonym Full Names: | fibrinogen-like 1 |
| NCBI Official Symbol: | FGL1 |
| NCBI Official Synonym Symbols: | HFREP1; HP-041; LFIRE1; LFIRE-1 |
| NCBI Protein Information: | fibrinogen-like protein 1; hepassocin; liver fibrinogen-related protein 1; hepatocellular carcinoma-related sequence; hepatocyte-derived fibrinogen-related protein 1 |
| UniProt Protein Name: | Fibrinogen-like protein 1 |
| UniProt Synonym Protein Names: | HP-041; Hepassocin; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; Liver fibrinogen-related protein 1; LFIRE-1 |
| Protein Family: | Fibrinogen-like protein |
| UniProt Gene Name: | FGL1 |
| UniProt Entry Name: | FGL1_HUMAN |
 | Western blot analysis of extracts of fetal liver, using FGL1 antibody (CAB10977). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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