Cell Biology Antibodies 14

Anti-FGF3 Antibody (CAB16850)

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SKU:
CAB16850
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-FGF3 Antibody
Antibody SKU:CAB16850
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FGF3 (NP_005238.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Rat
Positive Samples:Rat liver
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FGF3 (NP_005238.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGLI WLLL LSLL EPGW PAAG PGAR LRRD AGGR GGVY EHLG GAPR RRKL YCAT KYHL QLHP SGRV NGSL ENSA YSIL EITA VEVG IVAI RGLF SGRY LAMN
Gene ID:2248
Uniprot:P11487
Cellular Location:
Calculated MW:
Observed MW:27kDa
Anti-FGF3 Antibody (CAB16850)Western blot - FGF3 Rabbit pAb (CAB16850)
Synonyms:FGF3, HBGF-3, INT2
Background:The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.
NCBI Summary:The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. [provided by RefSeq, Jul 2008]
UniProt Code:P11487
NCBI GenInfo Identifier:4885233
NCBI Gene ID:2248
NCBI Accession:NP_005238.1
UniProt Related Accession:P11487
Molecular Weight:Predicted Molecular Mass: 27.8kDaAccurate Molecular Mass: 35kDa
NCBI Full Name:fibroblast growth factor 3
NCBI Synonym Full Names:fibroblast growth factor 3
NCBI Official Symbol:FGF3  
NCBI Official Synonym Symbols:INT2; HBGF-3  
NCBI Protein Information:fibroblast growth factor 3
UniProt Protein Name:Fibroblast growth factor 3
UniProt Synonym Protein Names:Heparin-binding growth factor 3; HBGF-3; Proto-oncogene Int-2
Protein Family:Von Hippel-Lindau disease tumor suppressor
UniProt Gene Name:FGF3  
UniProt Entry Name:FGF3_HUMAN
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