Cell Biology Antibodies 17
Anti-FGF21 Antibody (CAB3908)
- SKU:
- CAB3908
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-FGF21 Antibody |
Antibody SKU: | CAB3908 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human FGF21 |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | Mouse liver, Rat liver, Rat testis |
Immunogen: | A synthesized peptide derived from human FGF21 |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 26291 |
Uniprot: | Q9NSA1 |
Cellular Location: | |
Calculated MW: | 22kDa |
Observed MW: | 20KDa |
Synonyms: | |
Background: | Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue. [provided by RefSeq, Mar 2016] |
UniProt Protein Function: | FGF21: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Belongs to the heparin-binding growth factors family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: extracellular region Molecular Function:protein binding; growth factor activity; fibroblast growth factor receptor binding Biological Process: positive regulation of glucose import; cell-cell signaling; positive regulation of cell proliferation; positive regulation of low-density lipoprotein receptor biosynthetic process; signal transduction |
NCBI Summary: | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NSA1 |
NCBI GenInfo Identifier: | 13626703 |
NCBI Gene ID: | 26291 |
NCBI Accession: | Q9NSA1.1 |
UniProt Secondary Accession: | Q9NSA1,Q8N683, |
UniProt Related Accession: | Q9NSA1 |
Molecular Weight: | 22,300 Da |
NCBI Full Name: | Fibroblast growth factor 21 |
NCBI Synonym Full Names: | fibroblast growth factor 21 |
NCBI Official Symbol: | FGF21 |
NCBI Protein Information: | fibroblast growth factor 21 |
UniProt Protein Name: | Fibroblast growth factor 21 |
Protein Family: | Fibroblast growth factor |
UniProt Gene Name: | FGF21 |
UniProt Entry Name: | FGF21_HUMAN |
View AllClose