Neuroscience

Anti-FGF13 Antibody (CAB7895)

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SKU:
CAB7895
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience

Description

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Antibody Name:Anti-FGF13 Antibody
Antibody SKU:CAB7895
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human FGF13 (NP_004105.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse brain, Mouse heart, Mouse spinal cord, Rat brain, Rat heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human FGF13 (NP_004105.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAAA IASS LIRQ KRQA RERE KSNA CKCV SSPS KGKT SCDK NKLN VFSR VKLF GSKK RRRR RPEP QLKG IVTK LYSR QGYH LQLQ ADGT IDGT KDED STYT LFNL IPVG LRVV AIQG VQTK LYLA MNSE GYLY TSEL FTPE CKFK ESVF ENYY VTYS SMIY RQQQ SGRG WYLG LNKE GEIM KGNH VKKN KPAA HFLP KPLK VAMY KEPS LHDL TEFS RSGS GTPT KSRS VSGV LNGG KSMS HNES T
Gene ID:2258
Uniprot:Q92913
Cellular Location:Cell projection, Cytoplasm, Cytoplasm, Nucleus, dendrite, filopodium, growth cone, nucleolus
Calculated MW:21kDa/22kDa/25kDa/27kDa/28kDa
Observed MW:28kDa
Synonyms:FGF13, FGF-13, FGF2, FHF-2, FHF2
Background:The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini.
UniProt Protein Function:Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus.
NCBI Summary:The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008]
UniProt Code:Q92913
NCBI GenInfo Identifier:2494461
NCBI Gene ID:2258
NCBI Accession:Q92913.1
UniProt Secondary Accession:Q92913,O95830, Q9NZH9, Q9NZI0, B1AK18, B7Z4M7, B7Z8N0 D3DWH4,
UniProt Related Accession:Q92913
Molecular Weight:25,607 Da
NCBI Full Name:Fibroblast growth factor 13
NCBI Synonym Full Names:fibroblast growth factor 13
NCBI Official Symbol:FGF13  
NCBI Official Synonym Symbols:FGF2; FHF2; FHF-2; FGF-13  
NCBI Protein Information:fibroblast growth factor 13
UniProt Protein Name:Fibroblast growth factor 13
UniProt Synonym Protein Names:Fibroblast growth factor homologous factor 2; FHF-2
Protein Family:Fibroblast growth factor
UniProt Gene Name:FGF13  
UniProt Entry Name:FGF13_HUMAN
Anti-FGF13 Antibody (CAB7895)Western blot analysis of extracts of various cell lines, using FGF13 antibody (CAB7895) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-FGF13 Antibody (CAB7895)Immunohistochemistry of paraffin-embedded human stomach using FGF13 antibody (CAB7895) at dilution of 1:100 (40x lens).
Anti-FGF13 Antibody (CAB7895)Immunohistochemistry of paraffin-embedded rat brain using FGF13 antibody (CAB7895) at dilution of 1:100 (40x lens).
Anti-FGF13 Antibody (CAB7895)Immunohistochemistry of paraffin-embedded mouse kidney using FGF13 antibody (CAB7895) at dilution of 1:100 (40x lens).
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