Signal Transduction Antibodies 3
Anti-FGD5 Antibody (CAB7856)
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- SKU:
- CAB7856
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-FGD5 Antibody |
| Antibody SKU: | CAB7856 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1200 of human FGD5 (NP_689749.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1200 of human FGD5 (NP_689749.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | YLGL LSEN CLHS PRLA AAVR EFEQ SVQG GSQT AKHR LLRV VQRL FQYQ VLLT DYLN NLCP DSAE YDNT QGAL SLIS KVTD RAND SMEQ GENL QKLV HIEH SVRG QGDL LQPG REFL KEGT LMKV TGKN RRPR HLFL MNDV LLYT YPQK DGKY RLKN TLAV ANMK VSRP VMEK VPYA LKIE TSES CLML SASS CAER DEWY G |
| Gene ID: | 152273 |
| Uniprot: | Q6ZNL6 |
| Cellular Location: | Cell projection, Cytoplasm, Early endosome, Endoplasmic reticulum, Golgi apparatus, cytoskeleton, ruffle membrane |
| Calculated MW: | 61kDa/159kDa |
| Observed MW: | Refer to figures |
| Synonyms: | FGD5, ZFYVE23, FYVE |
| Background: |
| UniProt Protein Function: | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape. |
| UniProt Code: | Q6ZNL6 |
| NCBI GenInfo Identifier: | 23271578 |
| NCBI Gene ID: | 152273 |
| NCBI Accession: | BC035364 |
| UniProt Secondary Accession: | Q6ZNL6,Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4, B3KVQ3 |
| UniProt Related Accession: | Q6ZNL6 |
| Molecular Weight: | 61,238 Da |
| NCBI Full Name: | Homo sapiens FYVE, RhoGEF and PH domain containing 5, mRNA |
| NCBI Synonym Full Names: | FYVE, RhoGEF and PH domain containing 5 |
| NCBI Official Symbol: | FGD5 |
| NCBI Official Synonym Symbols: | ZFYVE23 |
| NCBI Protein Information: | FYVE, RhoGEF and PH domain-containing protein 5 |
| UniProt Protein Name: | FYVE, RhoGEF and PH domain-containing protein 5 |
| UniProt Synonym Protein Names: | Zinc finger FYVE domain-containing protein 23 |
| Protein Family: | FYVE, RhoGEF and PH domain-containing protein |
| UniProt Gene Name: | FGD5 |
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