Cell Biology Antibodies 15
Anti-FFAR2 Antibody (CAB18592)
- SKU:
- CAB18592
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-FFAR2 Antibody |
| Antibody SKU: | CAB18592 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-330 of human FFAR2 (NP_005297.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-330 of human FFAR2 (NP_005297.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2867 |
| Uniprot: | O15552 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | |
| Background: |
| UniProt Protein Function: | FFAR2: Receptor for short chain fatty acids through a G(i)- protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 19q13.1 Cellular Component: cell projection; integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; lipid binding; protein binding Biological Process: cell surface pattern recognition receptor signaling pathway; fat cell differentiation; G-protein coupled receptor protein signaling pathway; glucose homeostasis; leukocyte chemotaxis during inflammatory response; mucosal immune response; positive regulation of acute inflammatory response to non-antigenic stimulus; positive regulation of chemokine production; positive regulation of cytokine production during immune response; regulation of acute inflammatory response; sequestering of lipid |
| NCBI Summary: | This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. [provided by RefSeq, Apr 2009] |
| UniProt Code: | O15552 |
| NCBI GenInfo Identifier: | 3122160 |
| NCBI Gene ID: | 2867 |
| NCBI Accession: | O15552.1 |
| UniProt Secondary Accession: | O15552,Q4VAZ3, Q4VAZ5, Q4VBL5, B0M0J9, |
| UniProt Related Accession: | O15552 |
| Molecular Weight: | 37,144 Da |
| NCBI Full Name: | Free fatty acid receptor 2 |
| NCBI Synonym Full Names: | free fatty acid receptor 2 |
| NCBI Official Symbol: | FFAR2 |
| NCBI Official Synonym Symbols: | FFA2R; GPR43 |
| NCBI Protein Information: | free fatty acid receptor 2 |
| UniProt Protein Name: | Free fatty acid receptor 2 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 43 |
| Protein Family: | Free fatty acid receptor |
| UniProt Gene Name: | FFAR2 |
| UniProt Entry Name: | FFAR2_HUMAN |
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