UniProt Protein Function: | FEZF2: Transcription repressor. Required for the specification of corticospinal motor neurons and other subcerebral projection neurons. May play a role in layer and neuronal subtype-specific patterning of subcortical projections and axonal fasciculation. Controls the development of dendritic arborization and spines of large layer V pyramidal neurons. May be involved in innate immunity. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding; C2H2-type zinc finger protein; Transcription factor; Cell development/differentiation Chromosomal Location of Human Ortholog: 3p14.2 Biological Process: axon guidance; negative regulation of transcription, DNA-dependent |
UniProt Code: | Q8TBJ5 |
NCBI GenInfo Identifier: | 152032462 |
NCBI Gene ID: | 55079 |
NCBI Accession: | Q8TBJ5.2 |
UniProt Secondary Accession: | Q8TBJ5,Q9BZ91, Q9NWB9, A8K349, |
UniProt Related Accession: | Q8TBJ5 |
Molecular Weight: | 31,326 Da |
NCBI Full Name: | Fez family zinc finger protein 2 |
NCBI Synonym Full Names: | FEZ family zinc finger 2 |
NCBI Official Symbol: | FEZF2 |
NCBI Official Synonym Symbols: | FEZ; TOF; FEZL; FKSG36; ZFP312; ZNF312 |
NCBI Protein Information: | fez family zinc finger protein 2 |
UniProt Protein Name: | Fez family zinc finger protein 2 |
UniProt Synonym Protein Names: | Forebrain embryonic zinc finger-like protein 2; Zinc finger protein 312; Zinc finger protein Fez-like |
Protein Family: | Fez family zinc finger protein |
UniProt Gene Name: | FEZF2 |
UniProt Entry Name: | FEZF2_HUMAN |