Cell Biology Antibodies 17
Anti-Ferritin Heavy Chain Antibody (CAB19544)
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- SKU:
- CAB19544
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-Ferritin Heavy Chain Antibody |
| Antibody SKU: | CAB19544 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Ferritin Heavy Chain. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse brain, Mouse heart, Rat brain, Rat liver, U-251MG |
| Immunogen: | A synthesized peptide derived from human Ferritin Heavy Chain. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2495 |
| Uniprot: | P02794 |
| Cellular Location: | |
| Calculated MW: | 21kDa |
| Observed MW: | 21KDa |
 | Western blot - Ferritin Heavy Chain Rabbit mAb (CAB19544) |
| Synonyms: | FHC, FTH, FTHL6, HFE5, PIG15, PLIF, Ferritin, FTH1 |
| Background: | This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. |
| NCBI Summary: | This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P02794 |
| NCBI GenInfo Identifier: | 120516 |
| NCBI Gene ID: | 2495 |
| NCBI Accession: | P02794.2 |
| UniProt Secondary Accession: | P02794,Q3KRA8, Q3SWW1, B3KNR5, |
| UniProt Related Accession: | P02794 |
| Molecular Weight: | |
| NCBI Full Name: | Ferritin heavy chain |
| NCBI Synonym Full Names: | ferritin, heavy polypeptide 1 |
| NCBI Official Symbol: | FTH1 |
| NCBI Official Synonym Symbols: | FHC; FTH; HFE5; PLIF; FTHL6; PIG15 |
| NCBI Protein Information: | ferritin heavy chain |
| UniProt Protein Name: | Ferritin heavy chain |
| UniProt Synonym Protein Names: | Cell proliferation-inducing gene 15 protein |
| Protein Family: | Iron transporter |
| UniProt Gene Name: | FTH1 |
| UniProt Entry Name: | FRIH_HUMAN |
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