Metabolism Antibodies 3
Anti-FDX1 Antibody (CAB9815)
- SKU:
- CAB9815
- Product Type:
- Antibody
- Applications:
- WB
- Applications:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Description
Antibody Name: | Anti-FDX1 Antibody |
Antibody SKU: | CAB9815 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human FDX1 (NP_004100.1). |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | 293T, K-562, DU145 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human FDX1 (NP_004100.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MAAA GGAR LLRA ASAV LGGP AGRW LHHA GSRA GSSG LLRN RGPG GSAE ASRS LSVS ARAR SSSE DKIT VHFI NRDG ETLT TKGK VGDS LLDV VVEN NLDI DGFG ACEG TLAC STCH LIFE DHIY EKLD AITD EEND MLDL AYGL TDRS RLGC QICL TKSM DNMT VRVP ETVA DARQ SIDV GKTS |
Gene ID: | 2230 |
Uniprot: | P10109 |
Cellular Location: | Mitochondrion matrix |
Calculated MW: | 19kDa |
Observed MW: | 14kDa |
Synonyms: | FDX1, ADX, FDX, LOH11CR1D |
Background: | This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. |
UniProt Protein Function: | adrenodoxin: Participates in the synthesis of thyroid hormones. Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to cytochrome P450 cholesterol side-chain cleavage enzyme. Belongs to the adrenodoxin/putidaredoxin family. |
UniProt Protein Details: | Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 11q22 Cellular Component: mitochondrion; mitochondrial matrix Molecular Function:2 iron, 2 sulfur cluster binding; electron carrier activity; iron ion binding Biological Process: steroid metabolic process; cholesterol metabolic process; xenobiotic metabolic process; C21-steroid hormone biosynthetic process; hormone biosynthetic process; sterol metabolic process |
NCBI Summary: | This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011] |
UniProt Code: | P10109 |
NCBI GenInfo Identifier: | 4758352 |
NCBI Gene ID: | 2230 |
NCBI Accession: | NP_004100.1 |
UniProt Secondary Accession: | P10109,Q53YD6, B0YJ14, |
UniProt Related Accession: | P10109 |
Molecular Weight: | 19,393 Da |
NCBI Full Name: | adrenodoxin, mitochondrial |
NCBI Synonym Full Names: | ferredoxin 1 |
NCBI Official Symbol: | FDX1 |
NCBI Official Synonym Symbols: | ADX; FDX; LOH11CR1D |
NCBI Protein Information: | adrenodoxin, mitochondrial; ferredoxin-1; hepatoredoxin; adrenal ferredoxin; mitochondrial adrenodoxin |
UniProt Protein Name: | Adrenodoxin, mitochondrial |
UniProt Synonym Protein Names: | Adrenal ferredoxin; Ferredoxin-1; Hepatoredoxin |
Protein Family: | Adrenodoxin |
UniProt Gene Name: | FDX1 |
UniProt Entry Name: | ADX_HUMAN |
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