Cell Biology Antibodies 1
Anti-FCRL2 Antibody (CAB10324)
- SKU:
- CAB10324
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-FCRL2 Antibody |
| Antibody SKU: | CAB10324 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human FCRL2 |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | Raji |
| Immunogen: | Recombinant protein of human FCRL2 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 79368 |
| Uniprot: | Q96LA5 |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
| Calculated MW: | 15kDa/20kDa/22kDa/27kDa/55kDa |
| Observed MW: | 45kDa |
| Synonyms: | FCRL2, CD307b, FCRH2, IFGP4, IRTA4, SPAP1, SPAP1A, SPAP1B, SPAP1C |
| Background: | This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. |
| UniProt Protein Function: | FCRL2: May have an regulatory role in normal and neoplastic B cell development. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 1q23.1 Molecular Function:protein binding; SH3/SH2 adaptor activity |
| NCBI Summary: | This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Apr 2009] |
| UniProt Code: | Q96LA5 |
| NCBI GenInfo Identifier: | 68052374 |
| NCBI Gene ID: | 79368 |
| NCBI Accession: | Q96LA5.1 |
| UniProt Secondary Accession: | Q96LA5,Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6, A0N0M5, A1L307 A6NMS0, |
| UniProt Related Accession: | Q96LA5 |
| Molecular Weight: | 56kDa |
| NCBI Full Name: | Fc receptor-like protein 2 |
| NCBI Synonym Full Names: | Fc receptor like 2 |
| NCBI Official Symbol: | FCRL2 |
| NCBI Official Synonym Symbols: | FCRH2; IFGP4; IRTA4; SPAP1; CD307b; SPAP1A; SPAP1B; SPAP1C |
| NCBI Protein Information: | Fc receptor-like protein 2 |
| UniProt Protein Name: | Fc receptor-like protein 2 |
| UniProt Synonym Protein Names: | Fc receptor homolog 2; FcRH2; IFGP family protein 4; Immunoglobulin receptor translocation-associated protein 4; SH2 domain-containing phosphatase anchor protein 1; CD_antigen: CD307b |
| Protein Family: | Fc receptor-like protein |
| UniProt Gene Name: | FCRL2 |
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