Immunology Antibodies 2
Anti-FCGR2B Antibody (CAB7554)
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- SKU:
- CAB7554
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-FCGR2B Antibody |
| Antibody SKU: | CAB7554 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 241-310 of human FCGR2B (NP_003992.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | Human placenta |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 241-310 of human FCGR2B (NP_003992.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VVAL IYCR KKRI SALP GYPE CREM GETL PEKP ANPT NPDE ADKV GAEN TITY SLLM HPDA LEEP DDQN RI |
| Gene ID: | 2213 |
| Uniprot: | P31994 |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
| Calculated MW: | 31kDa/33kDa/34kDa |
| Observed MW: | 40kDa |
| Synonyms: | FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2 |
| Background: | The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. |
| NCBI Summary: | The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] |
| UniProt Code: | P31994 |
| NCBI GenInfo Identifier: | |
| NCBI Gene ID: | 2213 |
| NCBI Accession: | |
| UniProt Related Accession: | P31994 |
| Molecular Weight: | |
| NCBI Full Name: | |
| NCBI Synonym Full Names: | Fc fragment of IgG receptor IIb |
| NCBI Official Symbol: | FCGR2B |
| NCBI Official Synonym Symbols: | CD32; FCG2; CD32B; FCGR2; IGFR2; FCGR2C; FcRII-c |
| NCBI Protein Information: | low affinity immunoglobulin gamma Fc region receptor II-b |
| UniProt Protein Name: | |
| Protein Family: | CD320 antigen |
| UniProt Gene Name: |
 | Western blot analysis of extracts of human placenta, using FCGR2B antibody (CAB7554) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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