Immunology Antibodies 1

Anti-FCGR2B Antibody (CAB12553)

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SKU:
CAB12553
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology

Description

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Antibody Name:Anti-FCGR2B Antibody
Antibody SKU:CAB12553
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human FCGR2B
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse spleen, Rat liver
Immunogen:Recombinant protein of human FCGR2B
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:2213
Uniprot:P31994
Cellular Location:Cell membrane, Single-pass type I membrane protein
Calculated MW:31kDa/33kDa/34kDa
Observed MW:40kDa
Synonyms:FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2
Background:The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
NCBI Summary:The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
UniProt Code:P31994
NCBI GenInfo Identifier:
NCBI Gene ID:2213
NCBI Accession:
UniProt Related Accession:P31994
Molecular Weight:
NCBI Full Name:
NCBI Synonym Full Names:Fc fragment of IgG receptor IIb
NCBI Official Symbol:FCGR2B  
NCBI Official Synonym Symbols:CD32; FCG2; CD32B; FCGR2; IGFR2; FCGR2C; FcRII-c  
NCBI Protein Information:low affinity immunoglobulin gamma Fc region receptor II-b
UniProt Protein Name:
Protein Family:CD320 antigen
UniProt Gene Name:
Anti-FCGR2B Antibody (CAB12553)Western blot analysis of extracts of various cell lines, using FCGR2B antibody (CAB12553) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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