Cell Biology Antibodies 13

Anti-FCGR1B Antibody (CAB17483)

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SKU:
CAB17483
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-FCGR1B Antibody
Antibody SKU:CAB17483
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide of Human FCGR1B.
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:Mouse plasma
Immunogen:A synthetic peptide of Human FCGR1B.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:2210
Uniprot:Q92637
Cellular Location:
Calculated MW:
Observed MW:27kDa
Anti-FCGR1B Antibody (CAB17483)Western blot - FCGR1B Polyclonal Antibody (CAB17483)
Synonyms:CD64b, IGFRB, FCGR1B
Background:Three distinct, but closely related classes of receptors that bind the Fc portion of IgG have been identified (Fcgamma RI, II and III). The FcgammaRI family consists of three closely related genes termed A, B, and C. This gene encodes the low affinity FcgammaRIB receptor that may play an important role in humoral immune response. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
UniProt Protein Function:FCGR1B: May bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response. Belongs to the immunoglobulin superfamily. FCGR1 family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Receptor, misc.; Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p11.2

Cellular Component: early endosome membrane; plasma membrane

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; receptor-mediated endocytosis

NCBI Summary:Three distinct, but closely related classes of receptors that bind the Fc portion of IgG have been identified (Fcgamma RI, II and III). The FcgammaRI family consists of three closely related genes termed A, B, and C. This gene encodes the low affinity FcgammaRIB receptor that may play an important role in humoral immune response. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
UniProt Code:Q92637
NCBI GenInfo Identifier:74760649
NCBI Gene ID:2210
NCBI Accession:Q92637.1
UniProt Secondary Accession:Q92637,Q7KZ13, Q92638,
UniProt Related Accession:Q92637
Molecular Weight:22,136 Da
NCBI Full Name:High affinity immunoglobulin gamma Fc receptor IB
NCBI Synonym Full Names:Fc fragment of IgG receptor Ib
NCBI Official Symbol:FCGR1B  
NCBI Official Synonym Symbols:CD64b; IGFRB  
NCBI Protein Information:high affinity immunoglobulin gamma Fc receptor IB
UniProt Protein Name:High affinity immunoglobulin gamma Fc receptor IB
UniProt Synonym Protein Names:Fc-gamma RIB; FcRIB; hFcgammaRIB
Protein Family:High affinity immunoglobulin gamma Fc receptor
UniProt Gene Name:FCGR1B  
UniProt Entry Name:FCGRB_HUMAN
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