Name: Anti-FCGR1A Antibody (CAB1197)
Brand: Immunology Antibodies 1
SKU: CAB1197
Availability: OutOfStock

Antibody Name:	Anti-FCGR1A Antibody
Antibody SKU:	CAB1197
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 200-292 of human FCGR1A (NP_000557.1).

Application:	WB IHC
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:100
Reactivity:	Human, Mouse, Rat
Positive Samples:	LO2, U-937, Mouse liver, Rat liver

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 200-292 of human FCGR1A (NP_000557.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	SPLL EGNL VTLS CETK LLLQ RPGL QLYF SFYM GSKT LRGR NTSS EYQI LTAR REDS GLYW CEAA TEDG NVLK RSPE LELQ VLGL QLPT PVWF H
Gene ID:	2209
Uniprot:	P12314
Cellular Location:	Cell membrane, Single-pass type I membrane protein
Calculated MW:	38kDa/42kDa
Observed MW:	70-80kDa

Synonyms:	FCGR1A, CD64, CD64A, FCRI, IGFR1
Background:	This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.

UniProt Protein Function:	FCGR1A: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Belongs to the immunoglobulin superfamily. FCGR1 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Receptor, misc.; Membrane protein, integral Chromosomal Location of Human Ortholog: 1q21.2-q21.3 Cellular Component: early endosome membrane; plasma membrane; integral to membrane Molecular Function:protein binding; IgG binding; receptor signaling protein activity Biological Process: antigen processing and presentation of peptide antigen via MHC class I; cytokine and chemokine mediated signaling pathway; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; innate immune response; antigen processing and presentation of exogenous peptide antigen via MHC class I; immune response; signal transduction; phagocytosis, engulfment
NCBI Summary:	This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]
UniProt Code:	P12314
NCBI GenInfo Identifier:	50403717
NCBI Gene ID:	2209
NCBI Accession:	P12314.2
UniProt Related Accession:	P12314
Molecular Weight:
NCBI Full Name:	High affinity immunoglobulin gamma Fc receptor I
NCBI Synonym Full Names:	Fc fragment of IgG receptor Ia
NCBI Official Symbol:	FCGR1A
NCBI Official Synonym Symbols:	CD64; FCRI; CD64A; IGFR1
NCBI Protein Information:	high affinity immunoglobulin gamma Fc receptor I
UniProt Protein Name:	High affinity immunoglobulin gamma Fc receptor I
UniProt Synonym Protein Names:	Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD_antigen: CD64
UniProt Gene Name:	FCGR1A
UniProt Entry Name:	FCGR1_HUMAN

	Western blot analysis of extracts of various cell lines, using FCGR1A antibody (CAB1197) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
	Immunohistochemistry of paraffin-embedded rat kidney using FCGR1A Rabbit pAb (CAB1197) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded mouse kidney using FCGR1A Rabbit pAb (CAB1197) at dilution of 1:100 (40x lens).