Cell Biology Antibodies 7
Anti-FCER2 Antibody (CAB1839)
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- SKU:
- CAB1839
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-FCER2 Antibody |
| Antibody SKU: | CAB1839 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 48-321 of human FCER2 (NP_001993.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human, Mouse |
| Positive Samples: | MCF7 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 48-321 of human FCER2 (NP_001993.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DTTQ SLKQ LEER AARN VSQV SKNL ESHH GDQM AQKS QSTQ ISQE LEEL RAEQ QRLK SQDL ELSW NLNG LQAD LSSF KSQE LNER NEAS DLLE RLRE EVTK LRME LQVS SGFV CNTC PEKW INFQ RKCY YFGK GTKQ WVHA RYAC DDME GQLV SIHS PEEQ DFLT KHAS HTGS WIGL RNLD LKGE FIWV DGSH VDYS NWAP GEPT SRSQ GEDC VMMR GSGR WNDA FCDR KLGA WVCD RLAT CTPP ASEG SAES MGPD SRPD PDGR LPTP SAPL HS |
| Gene ID: | 2208 |
| Uniprot: | P06734 |
| Cellular Location: | Cell membrane, Lipid-anchor, Secreted, Single-pass type II membrane protein |
| Calculated MW: | 36kDa |
| Observed MW: | 36kDa |
| Synonyms: | FCER2, BLAST-2, CD23, CD23A, CLEC4J, FCE2, IGEBF |
| Background: | The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| UniProt Protein Function: | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). |
| NCBI Summary: | The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] |
| UniProt Code: | P06734 |
| NCBI GenInfo Identifier: | 119862 |
| NCBI Gene ID: | 2208 |
| NCBI Accession: | P06734.1 |
| UniProt Related Accession: | P06734 |
| Molecular Weight: | |
| NCBI Full Name: | Low affinity immunoglobulin epsilon Fc receptor |
| NCBI Synonym Full Names: | Fc fragment of IgE receptor II |
| NCBI Official Symbol: | FCER2 |
| NCBI Official Synonym Symbols: | CD23; FCE2; CD23A; IGEBF; CLEC4J; BLAST-2 |
| NCBI Protein Information: | low affinity immunoglobulin epsilon Fc receptor |
| UniProt Protein Name: | Low affinity immunoglobulin epsilon Fc receptor |
| UniProt Synonym Protein Names: | BLAST-2; C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor; CD_antigen: CD23Cleaved into the following 2 chains:Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form |
| UniProt Gene Name: | FCER2 |
| UniProt Entry Name: | FCER2_HUMAN |
 | Western blot analysis of extracts of MCF-7 cells, using FCER2 antibody (CAB1839) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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