Cell Biology Antibodies 13
Anti-FBXO28 Antibody (CAB17659)
- SKU:
- CAB17659
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-FBXO28 Antibody |
Antibody SKU: | CAB17659 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 91-312 of human FBXO28 (NP_055991.1). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Rat |
Positive Samples: | HT-29, PC-3, Rat testis |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 91-312 of human FBXO28 (NP_055991.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | CKRM DLVC QRML NQGF LKVE RYHN LCQK QVKA QLPR RESE RRNH SLAR HADI LAAV ETRL SLLN MTFM KYVD SNLC CFIP GKVI DEIY RVLR YVNS TRAP QRAH EVLQ ELRD ISSM AMEY FDEK IVPI LKRK LPGS DVSG RLMG SPPV PGPS AALT TMQL FSKQ NPSR QEVT KLQQ QVKT NGAG VTVL RREI SELR TKVQ EQQK QLQD QDQK LLEQ TQII GE |
Gene ID: | 23219 |
Uniprot: | Q9NVF7 |
Cellular Location: | |
Calculated MW: | |
Observed MW: | 45kDa |
Synonyms: | CENP-30, Fbx28, FBXO28 |
Background: | Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
UniProt Protein Function: | FBXO28: Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q42.11 Molecular Function:protein binding |
NCBI Summary: | Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9NVF7 |
NCBI GenInfo Identifier: | 59797970 |
NCBI Gene ID: | 23219 |
NCBI Accession: | Q9NVF7.1 |
UniProt Secondary Accession: | Q9NVF7,O75070, E9PEM8, |
UniProt Related Accession: | Q9NVF7 |
Molecular Weight: | 19,747 Da |
NCBI Full Name: | F-box only protein 28 |
NCBI Synonym Full Names: | F-box protein 28 |
NCBI Official Symbol: | FBXO28 |
NCBI Official Synonym Symbols: | Fbx28; CENP-30 |
NCBI Protein Information: | F-box only protein 28 |
UniProt Protein Name: | F-box only protein 28 |
Protein Family: | F-box only protein |
UniProt Gene Name: | FBXO28 |
UniProt Entry Name: | FBX28_HUMAN |