Cell Biology Antibodies 14
Anti-FBXO24 Antibody (CAB13770)
- SKU:
- CAB13770
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-FBXO24 Antibody |
Antibody SKU: | CAB13770 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human FBXO24 (NP_277041.1). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse |
Positive Samples: | MCF7 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human FBXO24 (NP_277041.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MGEK AVPL LRRR RVKR SCPS CGSE LGVE EKRG KGNP ISIQ LFPP ELVE HIIS FLPV RDLV ALGQ TCRY FHEV CDGE GVWR RICR RLSP RLQD QGSG VRPW KRAA ILNY TKGL YFQA FGGR RRCL SKSV APLL AHGY RRFL PTKD HVFI LD |
Gene ID: | 26261 |
Uniprot: | O75426 |
Cellular Location: | |
Calculated MW: | 36kDa/63kDa/64kDa/69kDa |
Observed MW: | 64kDa |
Synonyms: | FBXO24, FBX24 |
Background: | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Multiple transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | FBXO24: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 7q22 Molecular Function:protein binding |
NCBI Summary: | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009] |
UniProt Code: | O75426 |
NCBI GenInfo Identifier: | 51338744 |
NCBI Gene ID: | 26261 |
NCBI Accession: | O75426.2 |
UniProt Secondary Accession: | O75426,Q9H0G1, A4D2D4, B4DX91, B4DY42, |
UniProt Related Accession: | O75426 |
Molecular Weight: | 63,456 Da |
NCBI Full Name: | F-box only protein 24 |
NCBI Synonym Full Names: | F-box protein 24 |
NCBI Official Symbol: | FBXO24 |
NCBI Official Synonym Symbols: | FBX24 |
NCBI Protein Information: | F-box only protein 24 |
UniProt Protein Name: | F-box only protein 24 |
Protein Family: | F-box only protein |
UniProt Gene Name: | FBXO24 |
UniProt Entry Name: | FBX24_HUMAN |