Cell Biology Antibodies 3

Anti-FAM62B Antibody (CAB12833)

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SKU:
CAB12833
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-FAM62B Antibody
Antibody SKU:CAB12833
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 630-760 of human FAM62B (NP_065779.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:U-87MG, HT-29, Mouse liver, Mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 630-760 of human FAM62B (NP_065779.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:EKRE RPPD HQHS AQVK RPSV SKEG RKTS IKSH MSGS PGPG GSNT APST PVIG GSDK PGME EKAQ PPEA GPQG LHDL GRSS SSLL ASPG HISV KEPT PSIA SDIS LPIA TQEL RQRL RQLE NGTT LGQS PLG
Gene ID:57488
Uniprot:A0FGR8
Cellular Location:Cell membrane, Endoplasmic reticulum membrane, Multi-pass membrane protein, Peripheral membrane protein
Calculated MW:35kDa/59kDa/98kDa/102kDa/104kDa
Observed MW:102kDa
Synonyms:ESYT2, CHR2SYT, E-Syt2, FAM62B
Background:
UniProt Protein Function:ESYT2: May play a role as calcium-regulated intrinsic membrane protein. Belongs to the extended synaptotagmin family. 5 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 7q36.3

Cellular Component: endoplasmic reticulum membrane; extrinsic to internal side of plasma membrane; integral to plasma membrane; intrinsic to endoplasmic reticulum membrane; membrane

Molecular Function:cadherin binding; calcium ion binding; calcium-dependent phospholipid binding; identical protein binding; phosphatidylcholine binding; phosphatidylethanolamine binding; phosphoinositide binding; protein binding

Biological Process: glycosphingolipid metabolic process

UniProt Code:A0FGR8
NCBI GenInfo Identifier:121949310
NCBI Gene ID:57488
NCBI Accession:A0FGR8.1
UniProt Secondary Accession:A0FGR8,Q69YJ2, Q6UKI4, Q6ZTU0, Q6ZVU1, Q9BQS0, Q9NW47 Q9ULJ2, A4D229,
UniProt Related Accession:A0FGR8
Molecular Weight:102kDa
NCBI Full Name:Extended synaptotagmin-2
NCBI Synonym Full Names:extended synaptotagmin 2
NCBI Official Symbol:ESYT2  
NCBI Official Synonym Symbols:E-Syt2; FAM62B; CHR2SYT  
NCBI Protein Information:extended synaptotagmin-2
UniProt Protein Name:Extended synaptotagmin-2
UniProt Synonym Protein Names:Chr2Syt
Protein Family:Extended synaptotagmin
UniProt Gene Name:ESYT2  
Anti-FAM62B Antibody (CAB12833)Western blot analysis of extracts of various cell lines, using ESYT2 antibody (CAB12833) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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