Cell Biology Antibodies 15
Anti-FAM21C Antibody (CAB18559)
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- SKU:
- CAB18559
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-FAM21C Antibody |
| Antibody SKU: | CAB18559 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human FAM21C. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant protein of human FAM21C. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 253725 |
| Uniprot: | Q9Y4E1 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | FAM21A, FAM21C, VPEF |
| Background: |
| UniProt Protein Function: | FAM21C: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. In the complex, it probably mediates the recruitment of the complex to endosome membranes. Plays a role in fluid-phase endocytosis, a process exploited by vaccinia intracellular mature virus (IMV) to enter cells. As a result, may facilitate the penetration of IMV into cells. Belongs to the FAM21 family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 10q11.1 Cellular Component: early endosome membrane; early endosome; plasma membrane; endosome Molecular Function:protein binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-3,4,5-triphosphate binding; phosphatidylinositol-5-phosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol 3-phosphate binding Biological Process: protein transport; retrograde transport, endosome to Golgi |
| UniProt Code: | Q9Y4E1 |
| NCBI GenInfo Identifier: | 281182694 |
| NCBI Gene ID: | 253725 |
| NCBI Accession: | NP_001162577.1 |
| UniProt Secondary Accession: | Q9Y4E1,Q5SQU4, Q5SQU5, Q7L521, Q9UG79, B4DZQ6, B9EK53 F5H0J6, F5H871, |
| UniProt Related Accession: | Q9Y4E1 |
| Molecular Weight: | 140,144 Da |
| NCBI Full Name: | WASH complex subunit FAM21C isoform 2 |
| NCBI Synonym Full Names: | family with sequence similarity 21, member C |
| NCBI Official Symbol: | FAM21C |
| NCBI Official Synonym Symbols: | VPEF; FAM21A |
| NCBI Protein Information: | WASH complex subunit FAM21C |
| UniProt Protein Name: | WASH complex subunit FAM21C |
| UniProt Synonym Protein Names: | Vaccinia virus penetration factor; VPEF |
| Protein Family: | WASH complex |
| UniProt Gene Name: | FAM21C |
| UniProt Entry Name: | FA21C_HUMAN |
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