Epigenetics & Nuclear Signaling Antibodies 1
Anti-FAM208A Antibody (CAB13187)
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- SKU:
- CAB13187
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-FAM208A Antibody |
| Antibody SKU: | CAB13187 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 700-1000 of human FAM208A (NP_001106207.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | U-87MG, HeLa, Jurkat, HepG2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 700-1000 of human FAM208A (NP_001106207.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DTED MRSK TVLK RKLE DLPE NMRK LAKT SNLS ENCH LYEE SPQP IGSL GHDA DLRR QQQD TCNS GIAD IHRL FNWL SETL ANAR HSDA SLTD TVNK ALGL STDD AYEE LRQK HEYE LNST PDKK DYEQ PTCA KVEN AQFK GTQS LLLE VDAT SKYS VAIS TSEV GTDH KLHL KEDP NLIS VNNF EDCS LCPS VPIE HGFR RQQS KSNN VEET EIHW KLIP ITGG NARS PEDQ LGKH GEKQ TPGM KSPE EQLV CVPP QEAF PNDP RVIN RQRS SDYQ FPSS PFTD TLKG TTED DVLT GQVE E |
| Gene ID: | 23272 |
| Uniprot: | Q9UK61 |
| Cellular Location: | Chromosome, Nucleus |
| Calculated MW: | 139kDa/170kDa/182kDa/189kDa |
| Observed MW: | 189kDa |
| Synonyms: | FAM208A, C3orf63, RAP140, TASOR, se89-1 |
| Background: |
| UniProt Protein Function: | Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. |
| UniProt Code: | Q9UK61 |
| NCBI GenInfo Identifier: | 163838631 |
| NCBI Gene ID: | 23272 |
| NCBI Accession: | NP_001106207.1 |
| UniProt Secondary Accession: | Q9UK61,Q9H2F7, Q9UPP7, A1L3A4, B5ME28, |
| UniProt Related Accession: | Q9UK61 |
| Molecular Weight: | Calculated: 139kDa; 170kDa; 182kDa; 189kDaObserved: 190kDa |
| NCBI Full Name: | protein TASOR isoform a |
| NCBI Synonym Full Names: | family with sequence similarity 208 member A |
| NCBI Official Symbol: | FAM208A |
| NCBI Official Synonym Symbols: | TASOR; RAP140; se89-1; C3orf63 |
| NCBI Protein Information: | protein TASOR |
| UniProt Protein Name: | Protein TASOR |
| UniProt Synonym Protein Names: | CTCL tumor antigen se89-1 |
| Protein Family: | Protein |
| UniProt Gene Name: | FAM208A |
 | Western blot analysis of extracts of various cell lines, using FAM208A antibody (CAB13187) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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