Cell Biology Antibodies 13
Anti-FAM120A Antibody (CAB17658)
- SKU:
- CAB17658
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-FAM120A Antibody |
Antibody SKU: | CAB17658 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human FAM120A (NP_055427.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: | U-87MG, HeLa |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human FAM120A (NP_055427.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MGVQ GFQD YIEK HCPS AVVP VELQ KLAR GSLV GGGR QRPP QTPL RLLV DADN CLHR LYGG FYTD WVSG GQWN HMLG YLAA LAKA CFGG NIEL FVFF NGAL EKAR LHEW VKRQ GNER QTAQ QIVS HVQN KGTP PPKV WFLP |
Gene ID: | 23196 |
Uniprot: | Q9NZB2 |
Cellular Location: | |
Calculated MW: | 68kDa/71kDa/117kDa/121kDa/125kDa |
Observed MW: | 122kDa |
Synonyms: | C9orf10, HBVPTPAP, OSSA, FAM120A, DNAPTP1, DNAPTP5 |
Background: |
UniProt Protein Function: | FAM120A: May participate in mRNA transport in the cytoplasm. Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous- type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses. Belongs to the constitutive coactivator of PPAR-gamma family. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA-binding; Tumor suppressor Chromosomal Location of Human Ortholog: 9q22.31 Cellular Component: membrane; cytoplasm; plasma membrane |
UniProt Code: | Q9NZB2 |
NCBI GenInfo Identifier: | 158523294 |
NCBI Gene ID: | |
NCBI Accession: | Q9NZB2.2 |
Molecular Weight: | 122; 69; 117; 72; 125; 122kDa |
NCBI Full Name: | Constitutive coactivator of PPAR-gamma-like protein 1 |
UniProt Protein Name: | Constitutive coactivator of PPAR-gamma-like protein 1 |
UniProt Synonym Protein Names: | Oxidative stress-associated Src activator; Protein FAM120A |
Protein Family: | Constitutive coactivator of PPAR-gamma-like protein |
UniProt Gene Name: | FAM120A |
UniProt Entry Name: | F120A_HUMAN |