Cell Biology Antibodies 10
Anti-FABP6 Antibody (CAB6906)
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- SKU:
- CAB6906
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-FABP6 Antibody |
| Antibody SKU: | CAB6906 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human FABP6 (NP_001436.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | MCF7, A375 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human FABP6 (NP_001436.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAFT GKFE MESE KNYD EFMK LLGI SSDV IEKA RNFK IVTE VQQD GQDF TWSQ HYSG GHTM TNKF TVGK ESNI QTMG GKTF KATV QMEG GKLV VNFP NYHQ TSEI VGDK LVEV STIG GVTY ERVS KRLA |
| Gene ID: | 2172 |
| Uniprot: | P51161 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 14kDa/19kDa |
| Observed MW: | 18kDa |
| Synonyms: | FABP6, I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP |
| Background: | This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. |
| UniProt Protein Function: | FABP6: Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. 2 isoforms of the human protein are produced by alternative promoter. |
| UniProt Protein Details: | Protein type:Lipid-binding Chromosomal Location of Human Ortholog: 5q33.3-q34 Cellular Component: cytoplasm; cytosol Molecular Function:transporter activity; lipid binding Biological Process: bile acid and bile salt transport; negative regulation of cell proliferation; bile acid metabolic process; lipid metabolic process; transmembrane transport |
| NCBI Summary: | This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P51161 |
| NCBI GenInfo Identifier: | 1708457 |
| NCBI Gene ID: | 2172 |
| NCBI Accession: | P51161.2 |
| UniProt Secondary Accession: | P51161,Q07DR7, Q8TBI3, Q9UGI7, |
| UniProt Related Accession: | P51161 |
| Molecular Weight: | 128 |
| NCBI Full Name: | Gastrotropin |
| NCBI Synonym Full Names: | fatty acid binding protein 6, ileal |
| NCBI Official Symbol: | FABP6 |
| NCBI Official Synonym Symbols: | ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB |
| NCBI Protein Information: | gastrotropin; GT; intestinal 15 kDa protein; ileal lipid-binding protein; illeal lipid-binding protein; ileal bile acid binding protein |
| UniProt Protein Name: | Gastrotropin |
| UniProt Synonym Protein Names: | Fatty acid-binding protein 6; Ileal lipid-binding protein; ILBP; Intestinal 15 kDa protein; I-15P; Intestinal bile acid-binding protein; I-BABP |
| Protein Family: | Gastrotropin |
| UniProt Gene Name: | FABP6 |
| UniProt Entry Name: | FABP6_HUMAN |
 | Western blot analysis of extracts of various cell lines, using FABP6 antibody (CAB6906) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded mouse kidney using FABP6 antibody (CAB6906) at dilution of 1:200 (40x lens). |
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