Signal Transduction Antibodies 1
Anti-FABP5 Antibody (CAB0947)
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- SKU:
- CAB0947
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-FABP5 Antibody |
| Antibody SKU: | CAB0947 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human FABP5 (NP_001435.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human FABP5 (NP_001435.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MATV QQLE GRWR LVDS KGFD EYMK ELGV GIAL RKMG AMAK PDCI ITCD GKNL TIKT ESTL KTTQ FSCT LGEK FEET TADG RKTQ TVCN FTDG ALVQ HQEW |
| Gene ID: | 2171 |
| Uniprot: | Q01469 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 15kDa |
| Observed MW: | 14kDa |
| Synonyms: | FABP5, E-FABP, EFABP, KFABP, PA-FABP, PAFABP |
| Background: | This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. |
| UniProt Protein Function: | FABP5: High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
| UniProt Protein Details: | Protein type:Lipid-binding Chromosomal Location of Human Ortholog: 8q21.13 Cellular Component: nucleoplasm; cytoplasm; cytosol Molecular Function:protein binding; transporter activity; fatty acid binding; lipid binding Biological Process: epidermis development; phosphatidylcholine biosynthetic process; glucose metabolic process; lipid metabolic process; glucose transport |
| NCBI Summary: | This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011] |
| UniProt Code: | Q01469 |
| NCBI GenInfo Identifier: | 232081 |
| NCBI Gene ID: | 2171 |
| NCBI Accession: | Q01469.3 |
| UniProt Secondary Accession: | Q01469,B2R4K0, |
| UniProt Related Accession: | Q01469 |
| Molecular Weight: | 15,164 Da |
| NCBI Full Name: | Fatty acid-binding protein, epidermal |
| NCBI Synonym Full Names: | fatty acid binding protein 5 (psoriasis-associated) |
| NCBI Official Symbol: | FABP5 |
| NCBI Official Synonym Symbols: | EFABP; KFABP; E-FABP; PAFABP; PA-FABP |
| NCBI Protein Information: | fatty acid-binding protein, epidermal; epidermal-type fatty acid-binding protein; psoriasis-associated fatty acid-binding protein homolog |
| UniProt Protein Name: | Fatty acid-binding protein, epidermal |
| UniProt Synonym Protein Names: | Epidermal-type fatty acid-binding protein; E-FABP; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog |
| Protein Family: | Fatty acid-binding protein |
| UniProt Gene Name: | FABP5 |
| UniProt Entry Name: | FABP5_HUMAN |
 | Western blot analysis of extracts of 293T cells, using FABP5 antibody (CAB0947) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 3min. |
 | Immunohistochemistry of paraffin-embedded rat kidney using FABP5 antibody (CAB0947) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using FABP5 antibody (CAB0947) at dilution of 1:100 (40x lens). |
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