Anti-Ezrin/Radixin/Moesin Antibody (CAB21093)
- SKU:
- CAB21093
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
| Antibody Name: | Anti-Ezrin/Radixin/Moesin Antibody (CAB21093) |
| Antibody SKU: | CAB21093 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 487-586 of human Ezrin/Radixin/Moesin (NP_003370.2). |
| Application: | Western blotting |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, 293T, Mouse brain, PC-12 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 487-586 of human Ezrin/Radixin/Moesin (NP_003370.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ESLQ DEGA EPTG YSAE LSSE GIRD DRNE EKRI TEAE KNER VQRQ LLTL SSEL SQAR DENK RTHN DIIH NENM RQGR DKYK TLRQ IRQG NTKQ RIDE FEAL |
| Cellular Location: | |
| Calculated MW: | 69kDa/68kDa/67kDa |
| Observed MW: | 76KDa/80KDa |
| Synonyms: | CVL, CVIL, VIL2, HEL-S-105, DFNB24, HEL70, IMD50 |
| Background: | The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. |
 | Western blot analysis of extracts of various cell lines, using Ezrin/Radixin/Moesin antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 20s. |
 | Western blot analysis of extracts of various cell lines, using Ezrin/Radixin/Moesin antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 0. 8s. |
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