Description
Product Name: | EXOC7 Rabbit pAb |
Product Code: | CAB20345 |
Size: | 50uL, 100uL |
Synonyms: | BLOM4, EX070, EXO70, EXOC1, 2-5-3p, Exo70p, NEDSEBA, YJL085W |
Applications: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 506-735 of human EXOC7 (NP_001138769.1). |
Applications: | WB |
Recommended Dilutions: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 506-735 of human EXOC7 (NP_001138769.1). |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 23265 |
Uniprot: | Q9UPT5 |
Calculated MW: | 83kDa |
Observed MW: | Refer to figures |
UniProt Protein Function: | EXOC7: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. Belongs to the EXO70 family. 6 isoforms of the human protein are produced by alternative splicing. Protein type: Cytoskeletal Chromosomal Location of Human Ortholog: 17q25.1 Cellular Component: membrane; exocyst; plasma membrane; microtubule organizing center; cytosol Molecular Function: protein binding Biological Process: protein transport; cellular protein metabolic process; exocytosis; organelle organization and biogenesis |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011] |
UniProt Code: | Q9UPT5 |
NCBI GenInfo Identifier: | 38372889 |
NCBI Gene ID: | 23265 |
NCBI Accession: | Q9UPT5.3 |
UniProt Secondary Accession: | Q9UPT5 |
UniProt Related Accession: | Q9UPT5 |
Molecular Weight: | 74 kDa |
NCBI Full Name: | Exocyst complex component 7 |
NCBI Synonym Full Names: | exocyst complex component 7 |
NCBI Official Symbol: | EXOC7 |
NCBI Official Synonym Symbols: | BLOM4; EX070; EXO70; EXOC1; 2-5-3p; Exo70p; YJL085W |
NCBI Protein Information: | exocyst complex component 7 |
UniProt Protein Name: | Exocyst complex component 7 |
UniProt Synonym Protein Names: | Exocyst complex component Exo70 |
Protein Family: | Exocyst complex protein |
UniProt Gene Name: | EXOC7 |
UniProt Entry Name: | EXOC7_HUMAN |