Cell Biology Antibodies 9
Anti-EXOC3 Antibody (CAB4506)
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- SKU:
- CAB4506
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SEC6
- Synonyms:
- SEC6L1
- Synonyms:
- Sec6p
- Research Area:
- Cell Biology
Description
| Product Name: | EXOC3 Rabbit pAb |
| Product Code: | CAB4506 |
| Size: | 20uL, 100uL |
| Synonyms: | EXOC3, SEC6, SEC6L1, Sec6p, EXOC3 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthetic Peptide of human EXOC3 |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:1000 IHC 1:20 - 1:50 |
| Reactivity: | Human |
| Positive Samples: | A-431 |
| Immunogen: | A synthetic Peptide of human EXOC3 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 11336 |
| Uniprot: | O60645 |
| Calculated MW: | 73kDa/85kDa/86kDa |
| Observed MW: | 87kDa |
| UniProt Protein Function: | SEC6L1: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC6 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 5p15.33 Cellular Component: cytosol; exocyst; secretory granule membrane Molecular Function:protein binding; SNARE binding Biological Process: exocyst localization; exocytosis |
| NCBI Summary: | The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60645 |
| NCBI GenInfo Identifier: | 24418663 |
| NCBI Gene ID: | 11336 |
| NCBI Accession: | O60645.2 |
| UniProt Secondary Accession: | O60645,Q6P2E8, Q8TEN6, Q8WUW0, Q96DI4, |
| UniProt Related Accession: | O60645 |
| Molecular Weight: | 85,567 Da |
| NCBI Full Name: | Exocyst complex component 3 |
| NCBI Synonym Full Names: | exocyst complex component 3 |
| NCBI Official Symbol: | EXOC3 |
| NCBI Official Synonym Symbols: | SEC6; Sec6p; SEC6L1 |
| NCBI Protein Information: | exocyst complex component 3 |
| UniProt Protein Name: | Exocyst complex component 3 |
| UniProt Synonym Protein Names: | Exocyst complex component Sec6 |
| Protein Family: | Exocyst complex component |
| UniProt Gene Name: | EXOC3 |
| UniProt Entry Name: | EXOC3_HUMAN |
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