Immunology Antibodies 3

Anti-EXOC1 Antibody (CAB8749)

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SKU:
CAB8749
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology

Description

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Antibody Name:Anti-EXOC1 Antibody
Antibody SKU:CAB8749
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 645-894 of human EXOC1 (NP_001020095.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:HeLa, Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 645-894 of human EXOC1 (NP_001020095.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RNFD KCIS NQIR QMEE VKIS KKSK VGIL PFVA EFEE FAGL AESI FKNA ERRG DLDK AYTK LIRG VFVN VEKV ANES QKTP RDVV MMEN FHHI FATL SRLK ISCL EAEK KEAK QKYT DHLQ SYVI YSLG QPLE KLNH FFEG VEAR VAQG IREE EVSY QLAF NKQE LRKV IKEY PGKE VKKG LDNL YKKV DKHL CEEE NLLQ VVWH SMQD EFIR QYKH FEGL IARC YPGS GVTM EFTI QDIL DYCS SIAQ SH
Gene ID:55763
Uniprot:Q9NV70
Cellular Location:
Calculated MW:100kDa/101kDa
Observed MW:102kDa
Synonyms:EXOC1, BM-102, SEC3, SEC3L1, SEC3P
Background:The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described.
UniProt Code:Q9NV70
NCBI GenInfo Identifier:67944634
NCBI Gene ID:55763
NCBI Accession:NP_001020095.1
UniProt Secondary Accession:Q9NV70,Q8R3S6,
UniProt Related Accession:Q9NV70
Molecular Weight:100,283 Da
NCBI Full Name:exocyst complex component 1 isoform 1
NCBI Synonym Full Names:exocyst complex component 1
NCBI Official Symbol:EXOC1  
NCBI Official Synonym Symbols:SEC3; SEC3P; BM-102; SEC3L1  
NCBI Protein Information:exocyst complex component 1; SEC3-like 1; exocyst complex component Sec3
UniProt Protein Name:Exocyst complex component 1
UniProt Synonym Protein Names:Exocyst complex component Sec3
Protein Family:Exocyst complex component
UniProt Gene Name:EXOC1  
UniProt Entry Name:EXOC1_HUMAN
Anti-EXOC1 Polyclonal Antibody (CAB8749)Western blot analysis of extracts of HeLa cells, using EXOC1 Antibody (CAB8749) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
Anti-EXOC1 Polyclonal Antibody (CAB8749)Western blot analysis of extracts of mouse brain, using EXOC1 Antibody (CAB8749) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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