Epigenetics & Nuclear Signaling Antibodies 3
Anti-ETS2 Antibody (CAB16845)
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- SKU:
- CAB16845
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-ETS2 Antibody |
| Antibody SKU: | CAB16845 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of human ETS2. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: |
| Immunogen: | A synthetic peptide of human ETS2. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2114 |
| Uniprot: | P15036 |
| Cellular Location: | |
| Calculated MW: | 53kDa |
| Observed MW: | Refer to figures |
| Synonyms: | ETS2, ETS2IT1 |
| Background: | This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | Ets-2: a proto-oncogenic transcription factor homologous to the v-ets erythroblastosis virus E26 oncogene. A target of the Akt/JNK signaling pathway in macrophages. A PKC pathway activates ETS2, up-regulating GM-CSF in non-small lung carcinoma cells. |
| UniProt Protein Details: | Protein type:Transcription factor; Oncoprotein; DNA-binding Chromosomal Location of Human Ortholog: 21q22.2 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding; DNA binding; transcription factor activity; glucocorticoid receptor binding Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; cell differentiation; skeletal development |
| NCBI Summary: | This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
| UniProt Code: | P15036 |
| NCBI GenInfo Identifier: | 119645 |
| NCBI Gene ID: | 2114 |
| NCBI Accession: | P15036.1 |
| UniProt Secondary Accession: | P15036,A1A4L6, |
| UniProt Related Accession: | P15036 |
| Molecular Weight: | 469 |
| NCBI Full Name: | Protein C-ets-2 |
| NCBI Synonym Full Names: | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| NCBI Official Symbol: | ETS2 |
| NCBI Official Synonym Symbols: | ETS2IT1 |
| NCBI Protein Information: | protein C-ets-2; oncogene ETS-2; v-ets erythroblastosis virus E26 oncogene homolog 2; v-ets avian erythroblastosis virus E2 oncogene homolog 2 |
| UniProt Protein Name: | Protein C-ets-2 |
| Protein Family: | Protein |
| UniProt Gene Name: | ETS2 |
| UniProt Entry Name: | ETS2_HUMAN |
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