Cell Biology Antibodies 13
Anti-ESM1 Antibody (CAB17626)
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- SKU:
- CAB17626
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ESM1 Antibody |
| Antibody SKU: | CAB17626 |
| Antibody Size: | 20uL, 50 uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-184 of human ESM1 (NP_008967.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-184 of human ESM1 (NP_008967.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | WSNN YAVD CPQH CDSS ECKS SPRC KRTV LDDC GCCR VCAA GRGE TCYR TVSG MDGM KCGP GLRC QPSN GEDP FGEE FGIC KDCP YGTF GMDC RETC NCQS GICD RGTG KCLK FPFF QYSV TKSS NRFV SLTE HDMA SGDG NIVR EEVV KENA AGSP VMRK WLNP R |
| Gene ID: | 11082 |
| Uniprot: | Q9NQ30 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | endocan, ESM1 |
| Background: | This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
| UniProt Protein Function: | ESM1: May have potent implications in lung endothelial cell- leukocyte interactions. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 5q11.2 Cellular Component: extracellular region Molecular Function:integrin binding; insulin-like growth factor binding; hepatocyte growth factor receptor binding Biological Process: positive regulation of cell proliferation; sprouting angiogenesis; regulation of cell growth; angiogenesis |
| NCBI Summary: | This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
| UniProt Code: | Q9NQ30 |
| NCBI GenInfo Identifier: | 13431509 |
| NCBI Gene ID: | 11082 |
| NCBI Accession: | Q9NQ30.2 |
| UniProt Secondary Accession: | Q9NQ30,Q15330, Q3V4E3, Q96ES3, B2R4G3, |
| UniProt Related Accession: | Q9NQ30 |
| Molecular Weight: | 14,513 Da |
| NCBI Full Name: | Endothelial cell-specific molecule 1 |
| NCBI Synonym Full Names: | endothelial cell-specific molecule 1 |
| NCBI Official Symbol: | ESM1 |
| NCBI Official Synonym Symbols: | endocan |
| NCBI Protein Information: | endothelial cell-specific molecule 1; ESM-1 |
| UniProt Protein Name: | Endothelial cell-specific molecule 1 |
| Protein Family: | Endothelial cell-specific molecule |
| UniProt Gene Name: | ESM1 |
| UniProt Entry Name: | ESM1_HUMAN |
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