Anti-ERp29 Antibody (CAB19771)

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SKU:
CAB19771
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
C12orf8
Synonyms:
ERp28
Synonyms:
ERp31
Synonyms:
HEL-S-107
Synonyms:
PDI-DB
Synonyms:
PDIA9
Research Area:
Cell Biology

Description

Product Name:ERp29 Rabbit mAb
Product Code:CAB19771
Size:20uL, 50uL, 100uL
Synonyms:C12orf8, ERp28, ERp31, HEL-S-107, PDI-DB, PDIA9
Applications:WB, IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human ERp29
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:293T, HepG2, A-431, NIH/3T3, Mouse brain, Mouse kidney, Rat lung, Rat spleen, Rat kidney
Immunogen:A synthesized peptide derived from human ERp29
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:10961
Uniprot:P30040
Calculated MW:29kDa
Observed MW:30KDa
UniProt Protein Function:ERP29: Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER.
UniProt Protein Details:

Protein type:Chaperone

Chromosomal Location of Human Ortholog: 12q24.13

Cellular Component: cell surface; endoplasmic reticulum; membrane; smooth endoplasmic reticulum; transport vesicle

Molecular Function:chaperone binding; protein disulfide isomerase activity; protein homodimerization activity

Biological Process: activation of MAPK activity; intracellular protein transport; negative regulation of protein secretion; positive regulation of protein amino acid phosphorylation

NCBI Summary:This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
UniProt Code:P30040
NCBI GenInfo Identifier:6015110
NCBI Gene ID:10961
NCBI Accession:P30040.4
UniProt Secondary Accession:P30040,Q3MJC3, Q6FHT4, C9J183,
UniProt Related Accession:P30040
Molecular Weight:5,477 Da
NCBI Full Name:Endoplasmic reticulum resident protein 29
NCBI Synonym Full Names:endoplasmic reticulum protein 29
NCBI Official Symbol:ERP29  
NCBI Official Synonym Symbols:ERp28; ERp31; PDIA9; PDI-DB; C12orf8; HEL-S-107  
NCBI Protein Information:endoplasmic reticulum resident protein 29
UniProt Protein Name:Endoplasmic reticulum resident protein 29
UniProt Synonym Protein Names:Endoplasmic reticulum resident protein 28; ERp28; Endoplasmic reticulum resident protein 31; ERp31
Protein Family:Endoplasmic reticulum resident protein
UniProt Gene Name:ERP29  
UniProt Entry Name:ERP29_HUMAN
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