Epigenetics & Nuclear Signaling Antibodies 4
Anti-ERCC8 Antibody (CAB6884)
(No reviews yet)
Write a Review
- SKU:
- CAB6884
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-ERCC8 Antibody |
| Antibody SKU: | CAB6884 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human ERCC8 (NP_000073.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse testis |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human ERCC8 (NP_000073.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SCGC SSEF VFVP YGST IAVY TVYS GEQI TMLK GHYK TVDC CVFQ SNFQ ELYS GSRD CNIL AWVP SLYE PVPD DDET TTKS QLNP AFED AWSS SDEE G |
| Gene ID: | 1161 |
| Uniprot: | Q13216 |
| Cellular Location: | Nucleus |
| Calculated MW: | 23kDa/44kDa |
| Observed MW: | 44kDa |
| Synonyms: | ERCC8, CKN1, CSA, UVSS2 |
| Background: | This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene. |
| UniProt Code: | Q13216 |
| NCBI GenInfo Identifier: | 3121917 |
| NCBI Gene ID: | 1161 |
| NCBI Accession: | Q13216.1 |
| UniProt Secondary Accession: | Q13216,Q6FHX5, Q96GB9, B2RB64, |
| UniProt Related Accession: | Q13216 |
| Molecular Weight: | 396 |
| NCBI Full Name: | DNA excision repair protein ERCC-8 |
| NCBI Synonym Full Names: | excision repair cross-complementation group 8 |
| NCBI Official Symbol: | ERCC8 |
| NCBI Official Synonym Symbols: | CSA; CKN1; UVSS2 |
| NCBI Protein Information: | DNA excision repair protein ERCC-8; Cockayne syndrome WD-repeat protein CSA; cockayne syndrome WD repeat protein CSA; excision repair cross-complementing rodent repair deficiency, complementation group 8 |
| UniProt Protein Name: | DNA excision repair protein ERCC-8 |
| UniProt Synonym Protein Names: | Cockayne syndrome WD repeat protein CSA |
| Protein Family: | DNA excision repair protein |
| UniProt Gene Name: | ERCC8 |
| UniProt Entry Name: | ERCC8_HUMAN |
 | Western blot analysis of extracts of mouse testis, using ERCC8 Antibody (CAB6884) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
View AllClose
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
