Cell Biology Antibodies 13
Anti-EPN1 Antibody (CAB17695)
(No reviews yet)
Write a Review
- SKU:
- CAB17695
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-EPN1 Antibody |
| Antibody SKU: | CAB17695 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-180 of human EPN1 (NP_037465.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, Mouse lung, Mouse liver, Mouse kidney, Rat testis, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-180 of human EPN1 (NP_037465.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LVAL LRDE DRLR EERA HALK TKEK LAQT ATAS SAAV GSGP PPEA EQAW PQS |
| Gene ID: | 29924 |
| Uniprot: | Q9Y6I3 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 94kDa |
 | Western blot - EPN1 Rabbit pAb (CAB17695) |
| Synonyms: | EPN1 |
| Background: | This gene encodes a member of the epsin protein family. The encoded protein binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Loss of function of this gene is associated with reduced tumor growth and progression in certain cancer types. [provided by RefSeq, Mar 2016] |
| UniProt Protein Function: | epsin 1: Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis. Belongs to the epsin family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Vesicle Chromosomal Location of Human Ortholog: 19q13.42 Cellular Component: plasma membrane Molecular Function:protein binding Biological Process: negative regulation of epidermal growth factor receptor signaling pathway |
| NCBI Summary: | This gene encodes a member of the epsin protein family. The encoded protein binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Loss of function of this gene is associated with reduced tumor growth and progression in certain cancer types. [provided by RefSeq, Mar 2016] |
| UniProt Code: | Q9Y6I3 |
| NCBI GenInfo Identifier: | 332278179 |
| NCBI Gene ID: | 29924 |
| NCBI Accession: | Q9Y6I3.2 |
| UniProt Secondary Accession: | Q9Y6I3,Q86ST3, Q9HA18, |
| UniProt Related Accession: | Q9Y6I3 |
| Molecular Weight: | 57,504 Da |
| NCBI Full Name: | Epsin-1 |
| NCBI Synonym Full Names: | epsin 1 |
| NCBI Official Symbol: | EPN1 |
| NCBI Protein Information: | epsin-1 |
| UniProt Protein Name: | Epsin-1 |
| UniProt Synonym Protein Names: | EH domain-binding mitotic phosphoprotein; EPS-15-interacting protein 1 |
| UniProt Gene Name: | EPN1 |
| UniProt Entry Name: | EPN1_HUMAN |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक