Cell Biology Antibodies 1

Anti-ENTPD3 Antibody (CAB10424)

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SKU:
CAB10424
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ENTPD3 Antibody
Antibody SKU:CAB10424
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 45-366 of human ENTPD3 (NP_001278890.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 45-366 of human ENTPD3 (NP_001278890.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:IHKQ EVLP PGLK YGIV LDAG SSRT TVYV YQWP AEKE NNTG VVSQ TFKC SVKG SGIS SYGN NPQD VPRA FEEC MQKV KGQV PSHL HGST PIHL GATA GMRL LRLQ NETA ANEV LESI QSYF KSQP FDFR GAQI ISGQ EEGV YGWI TANY LMGN FLEK NLWH MWVH PHGV ETTG ALDL GGAS TQIS FVAG EKMD LNTS DIMQ VSLY GYVY TLYT HSFQ CYGR NEAE KKFL AMLL QNSP TKNH LTNP CYPR DYSI SFTM GHVF DSLC TVDQ RPES YNPN DVIT FEGT GDPS LCKE KVAS IFDF KACH DQET CSFD GVYQ PKIK GP
Gene ID:956
Uniprot:O75355
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:50kDa/59kDa
Observed MW:59kDa
Synonyms:ENTPD3, CD39L3, HB6, NTPDase-3
Background:This gene encodes a plasma membrane-bound divalent cation-dependent E-type nucleotidase. The encoded protein is involved in the regulation of extracellular levels of ATP by hydrolysis of it and other nucleotides. Multiple transcript variants have been described.
UniProt Protein Function:ENTPD3: Has a threefold preference for the hydrolysis of ATP over ADP. Belongs to the GDA1/CD39 NTPase family.
UniProt Protein Details:

Protein type:Hydrolase; EC 3.6.1.5; Membrane protein, integral; Phosphatase (non-protein); Nucleotide Metabolism - purine; Membrane protein, multi-pass; Nucleotide Metabolism - pyrimidine

Chromosomal Location of Human Ortholog: 3p21.3

Molecular Function:protein binding

NCBI Summary:This gene encodes a plasma membrane-bound divalent cation-dependent E-type nucleotidase. The encoded protein is involved in the regulation of extracellular levels of ATP by hydrolysis of it and other nucleotides. Multiple transcript variants have been described. [provided by RefSeq, May 2014]
UniProt Code:O75355
NCBI GenInfo Identifier:115311595
NCBI Gene ID:956
NCBI Accession:O75355.2
UniProt Secondary Accession:O75355,O60495, Q8N6K2, B2R8D0, G5E9N0,
UniProt Related Accession:O75355
Molecular Weight:50,762 Da
NCBI Full Name:Ectonucleoside triphosphate diphosphohydrolase 3
NCBI Synonym Full Names:ectonucleoside triphosphate diphosphohydrolase 3
NCBI Official Symbol:ENTPD3  
NCBI Official Synonym Symbols:HB6; CD39L3; NTPDase-3  
NCBI Protein Information:ectonucleoside triphosphate diphosphohydrolase 3
UniProt Protein Name:Ectonucleoside triphosphate diphosphohydrolase 3
UniProt Synonym Protein Names:CD39 antigen-like 3; Ecto-ATP diphosphohydrolase 3; Ecto-ATPDase 3; Ecto-ATPase 3; Ecto-apyrase 3; HB6
Protein Family:Ectonucleoside triphosphate diphosphohydrolase
UniProt Gene Name:ENTPD3  
UniProt Entry Name:ENTP3_HUMAN
Anti-ENTPD3 Antibody (CAB10424)Western blot analysis of extracts of mouse lung, using ENTPD3 antibody (CAB10424) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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