Cell Biology Antibodies 10
Anti-ENTPD2 Antibody (CAB6584)
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- SKU:
- CAB6584
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ENTPD2 Antibody |
| Antibody SKU: | CAB6584 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-268 of human ENTPD2 (NP_982293.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-268 of human ENTPD2 (NP_982293.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PTRD VREP PALK YGIV LDAG SSHT SMFI YKWP ADKE NDTG IVGQ HSSC DVPG GGIS SYAD NPSG ASQS LVGC LEQA LQDV PKER HAGT PLYL GATA GMRL LNLT NPEA STSV LMAV THTL TQYP FDFR GARI LSGQ EEGV FGWV TANY LLEN FIKY GWVG RWFR PRKG TLGA MDLG GAST QITF ETTS PAED RASE VQLH LYGQ HYRV YTHS FLCY GRDQ VLQR LLAS ALQT HGFH PCWP R |
| Gene ID: | 954 |
| Uniprot: | Q9Y5L3 |
| Cellular Location: | Cell membrane, Endoplasmic reticulum membrane, Multi-pass membrane protein |
| Calculated MW: | 48kDa/51kDa/53kDa |
| Observed MW: | Refer to Figures |
| Synonyms: | ENTPD2, CD39L1, NTPDase-2 |
| Background: | The protein encoded by this gene is the type 2 enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). E-NTPDases are a family of ecto-nucleosidases that hydrolyze 5'-triphosphates. This ecto-ATPase is an integral membrane protein. Alternative splicing of this gene results in multiple transcript variants. |
| UniProt Protein Function: | ENTPD2: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP. Belongs to the GDA1/CD39 NTPase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.6.1.-; Nucleotide Metabolism - purine; Extracellular matrix; Membrane protein, integral; Membrane protein, multi-pass; Hydrolase Chromosomal Location of Human Ortholog: 9q34 Cellular Component: endoplasmic reticulum membrane; integral to membrane; plasma membrane; basal lamina Molecular Function:nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; ATP binding Biological Process: platelet activation; G-protein coupled receptor protein signaling pathway; purine ribonucleoside diphosphate catabolic process |
| NCBI Summary: | The protein encoded by this gene is the type 2 enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). E-NTPDases are a family of ecto-nucleosidases that hydrolyze 5'-triphosphates. This ecto-ATPase is an integral membrane protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y5L3 |
| NCBI GenInfo Identifier: | 18203633 |
| NCBI Gene ID: | 954 |
| NCBI Accession: | Q9Y5L3.1 |
| UniProt Secondary Accession: | Q9Y5L3,O15464, Q5SPY6, Q5SPY7, |
| UniProt Related Accession: | Q9Y5L3 |
| Molecular Weight: | 495 |
| NCBI Full Name: | Ectonucleoside triphosphate diphosphohydrolase 2 |
| NCBI Synonym Full Names: | ectonucleoside triphosphate diphosphohydrolase 2 |
| NCBI Official Symbol: | ENTPD2 |
| NCBI Official Synonym Symbols: | CD39L1; NTPDase-2 |
| NCBI Protein Information: | ectonucleoside triphosphate diphosphohydrolase 2; NTPDase 2; ecto-ATPase 2; ecto-ATPDase 2; CD39 antigen-like 1; ecto-ATP diphosphohydrolase 2 |
| UniProt Protein Name: | Ectonucleoside triphosphate diphosphohydrolase 2 |
| UniProt Synonym Protein Names: | CD39 antigen-like 1; Ecto-ATP diphosphohydrolase 2; Ecto-ATPDase 2; Ecto-ATPase 2 |
| Protein Family: | Ectonucleoside triphosphate diphosphohydrolase |
| UniProt Gene Name: | ENTPD2 |
| UniProt Entry Name: | ENTP2_HUMAN |
 | Immunofluorescence analysis of A549 cells using ENTPD2 antibody (CAB6584). Blue: DAPI for nuclear staining. |
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