Cell Biology Antibodies 10

Anti-ENPEP Antibody (CAB6905)

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SKU:
CAB6905
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ENPEP Antibody
Antibody SKU:CAB6905
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 708-957 of human ENPEP (NP_001968.3).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 708-957 of human ENPEP (NP_001968.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DDKE LYPM IEEY FQGQ VKPI ADSL GWND AGDH VTKL LRSS VLGF ACKM GDRE ALNN ASSL FEQW LNGT VSLP VNLR LLVY RYGM QNSG NEIS WNYT LEQY QKTS LAQE KEKL LYGL ASVK NVTL LSRY LDLL KDTN LIKT QDVF TVIR YISY NSYG KNMA WNWI QLNW DYLV NRYT LNNR NLGR IVTI AEPF NTEL QLWQ MESF FAKY PQAG AGEK PREQ VLET VKNN IEWL KQHR NTIR EWFF NLLE SG
Gene ID:2028
Uniprot:Q07075
Cellular Location:Membrane, Single-pass type II membrane protein
Calculated MW:109kDa
Observed MW:109-160kDa
Synonyms:ENPEP, APA, CD249, gp160
Background:
UniProt Protein Function:ENPEP: Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells. Belongs to the peptidase M1 family.
UniProt Protein Details:

Protein type:EC 3.4.11.7; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: apical part of cell; apical plasma membrane; brush border; cytoplasmic vesicle; external side of plasma membrane; lysosomal membrane; plasma membrane

Molecular Function:aminopeptidase activity; metallopeptidase activity; peptide binding; zinc ion binding

Biological Process: angiogenesis; angiotensin maturation; cell migration; cell proliferation; glomerulus development; peptide catabolic process; regulation of systemic arterial blood pressure by renin-angiotensin

UniProt Code:Q07075
NCBI GenInfo Identifier:296439445
NCBI Gene ID:2028
NCBI Accession:Q07075.3
UniProt Secondary Accession:Q07075,Q504U2,
UniProt Related Accession:Q07075
Molecular Weight:109,244 Da
NCBI Full Name:Glutamyl aminopeptidase
NCBI Synonym Full Names:glutamyl aminopeptidase
NCBI Official Symbol:ENPEP  
NCBI Official Synonym Symbols:APA; CD249; gp160  
NCBI Protein Information:glutamyl aminopeptidase
UniProt Protein Name:Glutamyl aminopeptidase
UniProt Synonym Protein Names:Aminopeptidase A; AP-A; Differentiation antigen gp160; CD_antigen: CD249
UniProt Gene Name:ENPEP  
UniProt Entry Name:AMPE_HUMAN
Anti-ENPEP Antibody (CAB6905)Western blot analysis of extracts of mouse lung, using ENPEP antibody (CAB6905) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
Anti-ENPEP Antibody (CAB6905)Immunohistochemistry of paraffin-embedded rat kidney using ENPEP antibody (CAB6905) at dilution of 1:200 (40x lens).
Anti-ENPEP Antibody (CAB6905)Immunohistochemistry of paraffin-embedded human prostate using ENPEP antibody (CAB6905) at dilution of 1:200 (40x lens).
Anti-ENPEP Antibody (CAB6905)Immunohistochemistry of paraffin-embedded human stomach using ENPEP antibody (CAB6905) at dilution of 1:200 (40x lens).
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