Cell Biology Antibodies 2
Anti-ENPEP Antibody (CAB12339)
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- SKU:
- CAB12339
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ENPEP Antibody |
| Antibody SKU: | CAB12339 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 850-950 of human ENPEP (NP_001968.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | 293T, LO2, HT-29, Mouse liver |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 850-950 of human ENPEP (NP_001968.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VFTV IRYI SYNS YGKN MAWN WIQL NWDY LVNR YTLN NRNL GRIV TIAE PFNT ELQL WQME SFFA KYPQ AGAG EKPR EQVL ETVK NNIE WLKQ HRNT IREW F |
| Gene ID: | 2028 |
| Uniprot: | Q07075 |
| Cellular Location: | Membrane, Single-pass type II membrane protein |
| Calculated MW: | 109kDa |
| Observed MW: | 109kDa |
| Synonyms: | ENPEP, APA, CD249, gp160 |
| Background: |
| UniProt Protein Function: | ENPEP: Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells. Belongs to the peptidase M1 family. |
| UniProt Protein Details: | Protein type:EC 3.4.11.7; Membrane protein, integral; Protease Chromosomal Location of Human Ortholog: 4q25 Cellular Component: apical part of cell; apical plasma membrane; brush border; cytoplasmic vesicle; external side of plasma membrane; lysosomal membrane; plasma membrane Molecular Function:aminopeptidase activity; metallopeptidase activity; peptide binding; zinc ion binding Biological Process: angiogenesis; angiotensin maturation; cell migration; cell proliferation; glomerulus development; peptide catabolic process; regulation of systemic arterial blood pressure by renin-angiotensin |
| UniProt Code: | Q07075 |
| NCBI GenInfo Identifier: | 296439445 |
| NCBI Gene ID: | 2028 |
| NCBI Accession: | Q07075.3 |
| UniProt Secondary Accession: | Q07075,Q504U2, |
| UniProt Related Accession: | Q07075 |
| Molecular Weight: | 109,244 Da |
| NCBI Full Name: | Glutamyl aminopeptidase |
| NCBI Synonym Full Names: | glutamyl aminopeptidase |
| NCBI Official Symbol: | ENPEP |
| NCBI Official Synonym Symbols: | APA; CD249; gp160 |
| NCBI Protein Information: | glutamyl aminopeptidase |
| UniProt Protein Name: | Glutamyl aminopeptidase |
| UniProt Synonym Protein Names: | Aminopeptidase A; AP-A; Differentiation antigen gp160; CD_antigen: CD249 |
| UniProt Gene Name: | ENPEP |
| UniProt Entry Name: | AMPE_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ENPEP antibody (CAB12339) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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