Name: Anti-ENO1 Antibody (CAB16842)
Brand: Metabolism Antibodies 3
SKU: CAB16842
Availability: OutOfStock

Antibody Name:	Anti-ENO1 Antibody
Antibody SKU:	CAB16842
Antibody Size:	20uL, 50 uL
Application:	WB IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-434 of human ENO1 (NP_001419.1).

Application:	WB IF
Recommended Dilution:	WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:	Human, Mouse, Rat
Positive Samples:	SH-SY5Y, MCF7, HeLa, Mouse testis, Mouse brain

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-434 of human ENO1 (NP_001419.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MSIL KIHA REIF DSRG NPTV EVDL FTSK GLFR AAVP SGAS TGIY EALE LRDN DKTR YMGK GVSK AVEH INKT IAPA LVSK KLNV TEQE KIDK LMIE MDGT ENKS KFGA NAIL GVSL AVCK AGAV EKGV PLYR HIAD LAGN SEVI LPVP AFNV INGG SHAG NKLA MQEF MILP VGAA NFRE AMRI GAEV YHNL KNVI KEKY GKDA TNVG DEGG FAPN ILEN KEGL ELLK TAIG KAGY TDKV VIGM DVAA SEFF RSGK YDLD FKSP DDPS RYIS PDQL ADLY KSFI KDYP VVSI EDPF DQDD WGAW QKFT ASAG IQVV GDDL TVTN PKRI AKAV NEKS CNCL LLKV NQIG SVTE SLQA CKLA QANG WGVM VSHR SGET EDTF IADL VVGL CTGQ IKTG APCR SERL AKYN QLLR IEEE LGSK AKFA GRNF RNPL AK
Gene ID:	2023
Uniprot:	P06733
Cellular Location:	Cell membrane, Cytoplasm, M line, Nucleus, myofibril, sarcomere
Calculated MW:	36kDa/47kDa
Observed MW:	47kDa

Western blot - ENO1 Rabbit pAb (CAB16842)

Synonyms:

ENO1, ENO1L1, HEL-S-17, MPB1, NNE, PPH, enolase 1

Background:

This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.

UniProt Protein Function:	ENO1: an abundant cytoplasmic enzyme with 2-phospho-D-glycerate hydro-lyase activity. A target of excess protein nitration in Alzheimer disease (AD) brain. Tau-crystallin, a structural lens protein, is produced from an alternative translation start in the enolase gene.
UniProt Protein Details:	Protein type:Transcription, coactivator/corepressor; EC 4.2.1.11; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Lyase Chromosomal Location of Human Ortholog: 1p36.2 Cellular Component: cytoplasm; cytosol; extracellular space; M band; membrane; nucleus; phosphopyruvate hydratase complex; plasma membrane Molecular Function:DNA binding; GTPase binding; magnesium ion binding; phosphopyruvate hydratase activity; protein binding; transcription corepressor activity; transcription factor activity Biological Process: carbohydrate metabolic process; gluconeogenesis; glucose metabolic process; negative regulation of cell growth; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; response to virus; transcription, DNA-dependent
NCBI Summary:	This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]
UniProt Code:	P06733
NCBI GenInfo Identifier:	119339
NCBI Gene ID:	2023
NCBI Accession:	P06733.2
UniProt Secondary Accession:	P06733,P22712, Q16704, Q4TUS4, Q53FT9, Q53HR3, Q658M5 Q6GMP2, Q71V37, Q7Z3V6, Q8WU71, B2RD59,
UniProt Related Accession:	P06733
Molecular Weight:	36,928 Da
NCBI Full Name:	Alpha-enolase
NCBI Synonym Full Names:	enolase 1, (alpha)
NCBI Official Symbol:	ENO1
NCBI Official Synonym Symbols:	NNE; PPH; MPB1; ENO1L1; HEL-S-17
NCBI Protein Information:	alpha-enolase; c-myc promoter-binding protein-1
UniProt Protein Name:	Alpha-enolase
UniProt Synonym Protein Names:	2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MBP-1; MPB-1; Non-neural enolase; NNE; Phosphopyruvate hydratase; Plasminogen-binding protein
UniProt Gene Name:	ENO1
UniProt Entry Name:	ENOA_HUMAN

Antibodies	ELISA Kits
Anti-ENO1 Antibody (CAB1033)[KO Validated]	Human NNE (Non-Neuronal Enolase) CLIA Kit (HUES00718)
Anti-ENO1 Antibody (CAB11448)	Human NNE (Non-Neuronal Enolase) ELISA Kit (HUES02320)
Anti-ENO1 Antibody (CAB16841)	Human Alpha-enolase (ENO1) ELISA Kit
ENO1 Antibody (PACO09090)