Cell Biology Antibodies 17
Anti-Endo G Antibody (CAB8801)
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- SKU:
- CAB8801
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-Endo G Antibody |
| Antibody SKU: | CAB8801 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Endo G |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SH-SY5Y, Mouse liver, Rat liver, Rat skeletal muscle, Rat heart |
| Immunogen: | A synthesized peptide derived from human Endo G |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2021 |
| Uniprot: | Q14249 |
| Cellular Location: | Mitochondrion |
| Calculated MW: | 30kDa |
| Observed MW: | 30KDa |
| Synonyms: | ENDOG, endonuclease G |
| Background: | The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | ENDOG: Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. Homodimer. Belongs to the DNA/RNA non-specific endonuclease family. |
| UniProt Protein Details: | Protein type:EC 3.1.30.-; Ribonuclease; Deoxyribonuclease; Apoptosis; Mitochondrial Chromosomal Location of Human Ortholog: 9q34.1 Cellular Component: mitochondrion Molecular Function:protein binding; nuclease activity; nucleic acid binding; metal ion binding; endonuclease activity Biological Process: response to antibiotic; positive regulation of apoptosis; in utero embryonic development; DNA fragmentation during apoptosis; DNA recombination |
| NCBI Summary: | The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q14249 |
| NCBI GenInfo Identifier: | 24638471 |
| NCBI Gene ID: | 2021 |
| NCBI Accession: | Q14249.3 |
| UniProt Secondary Accession: | Q14249,Q5T281, Q9BSP2, |
| UniProt Related Accession: | Q14249 |
| Molecular Weight: | 32,620 Da |
| NCBI Full Name: | Endonuclease G, mitochondrial |
| NCBI Synonym Full Names: | endonuclease G |
| NCBI Official Symbol: | ENDOG |
| NCBI Protein Information: | endonuclease G, mitochondrial; endo G; mitochondrial endonuclease G |
| UniProt Protein Name: | Endonuclease G, mitochondrial |
| Protein Family: | Endoglin |
| UniProt Gene Name: | ENDOG |
| UniProt Entry Name: | NUCG_HUMAN |
 | Western blot - Endo G Rabbit mAb (CAB8801) |
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