Cell Biology Antibodies 13
Anti-EN2 Antibody (CAB17480)
- SKU:
- CAB17480
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-EN2 Antibody |
Antibody SKU: | CAB17480 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthetic peptide of Human EN2. |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | U-87MG, Mouse brain, Rat brain |
Immunogen: | A synthetic peptide of Human EN2. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 2020 |
Uniprot: | P19622 |
Cellular Location: | |
Calculated MW: | |
Observed MW: | 33kDa |
Synonyms: | EN2 |
Background: | Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008] |
UniProt Protein Function: | En-2: Genetic variations in EN2 may be associated with susceptibility to autism. Belongs to the engrailed homeobox family. |
UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 7q36 Cellular Component: nucleus Biological Process: multicellular organismal development Disease: Autism, Susceptibility To, 10 |
NCBI Summary: | Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008] |
UniProt Code: | P19622 |
NCBI GenInfo Identifier: | 21903415 |
NCBI Gene ID: | 2020 |
NCBI Accession: | P19622.3 |
UniProt Secondary Accession: | P19622,Q549U3, Q9UD58, A4D252, |
UniProt Related Accession: | P19622 |
Molecular Weight: | 34,211 Da |
NCBI Full Name: | Homeobox protein engrailed-2 |
NCBI Synonym Full Names: | engrailed homeobox 2 |
NCBI Official Symbol: | EN2 |
NCBI Protein Information: | homeobox protein engrailed-2 |
UniProt Protein Name: | Homeobox protein engrailed-2 |
Protein Family: | Homeobox protein |
UniProt Gene Name: | EN2 |
UniProt Entry Name: | HME2_HUMAN |