Cell Biology Antibodies 4
Anti-EML2 Antibody (CAB14218)
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- SKU:
- CAB14218
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-EML2 Antibody |
| Antibody SKU: | CAB14218 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-415 of human EML2 (NP_036287.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse brain, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-415 of human EML2 (NP_036287.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LHVL GLGV FDRA VCCV GFSK SNGG NLLC AVDE SNDH MLSV WDWA KETK VVDV KCSN EAVL VATF HPTD PTVL ITCG KSHI YFWT LEGG SLSK RQGL FEKH EKPK YVLC VTFL EGGD VVTG DSGG NLYV WGKG GNRI TQAV LGAH DGGV FGLC ALRD GTLV SGGG RDRR VVLW GSDY SKLQ EVEV PEDF GPVR TVAE GHGD TLYV GTTR NSIL QGSV HTGF SLLV QGHV EELW GLAT HPSR AQFV TCGQ DKLV HLWS SDSH QPLW SR |
| Gene ID: | 24139 |
| Uniprot: | O95834 |
| Cellular Location: | Cytoplasm, cytoskeleton, spindle |
| Calculated MW: | 70kDa/86kDa/92kDa |
| Observed MW: | 71kDa |
| Synonyms: | EML2, ELP70, EMAP-2, EMAP2 |
| Background: |
| UniProt Protein Function: | EML2: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic. Belongs to the WD repeat EMAP family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 19q13.32 Cellular Component: microtubule; microtubule associated complex; cytoplasm Molecular Function:protein C-terminus binding; tubulin binding; microtubule binding; receptor binding Biological Process: sensory perception of sound; visual perception; negative regulation of microtubule polymerization |
| UniProt Code: | O95834 |
| NCBI GenInfo Identifier: | 17374910 |
| NCBI Gene ID: | 24139 |
| NCBI Accession: | O95834.1 |
| UniProt Secondary Accession: | O95834,Q59EN8, Q8N5A2, Q9UG50, B7Z3I2, B7Z3Q9, K7ERL7 |
| UniProt Related Accession: | O95834 |
| Molecular Weight: | 649 |
| NCBI Full Name: | Echinoderm microtubule-associated protein-like 2 |
| NCBI Synonym Full Names: | echinoderm microtubule associated protein like 2 |
| NCBI Official Symbol: | EML2 |
| NCBI Official Synonym Symbols: | ELP70; EMAP2; EMAP-2 |
| NCBI Protein Information: | echinoderm microtubule-associated protein-like 2; microtubule-associated protein like echinoderm EMAP; echinoderm MT-associated protein (EMAP)-like protein 70 |
| UniProt Protein Name: | Echinoderm microtubule-associated protein-like 2 |
| Protein Family: | Echinoderm microtubule-associated protein |
| UniProt Gene Name: | EML2 |
| UniProt Entry Name: | EMAL2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using EML2 Rabbit pAb (CAB14218) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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