Cell Biology Antibodies 1

Anti-EMC1 Antibody (CAB10290)

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SKU:
CAB10290
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-EMC1 Antibody
Antibody SKU:CAB10290
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 885-965 of human EMC1 (NP_055862.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:100 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Jurkat, LO2, HL-60
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 885-965 of human EMC1 (NP_055862.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:IPTE QSRE ENLI PYSP DVQI HAER FINY NQTV SRMR GIYT APSG LEST CLVV AYGL DIYQ TRVY PSKQ FDVL KDDY DYVL I
Gene ID:23065
Uniprot:Q8N766
Cellular Location:Membrane, Single-pass type I membrane protein
Calculated MW:109kDa/111kDa
Observed MW:112kDa
Synonyms:EMC1, CAVIPMR, KIAA0090
Background:This gene encodes a single-pass type I transmembrane protein, which is a subunit of the endoplasmic reticulum membrane protein complex (EMC). Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:EMC1: a single-pass type I transmembrane protein, which is a subunit of the endoplasmic reticulum membrane protein complex (EMC). Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2012]
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.13

Cellular Component: integral to membrane

Disease: Cerebellar Atrophy, Visual Impairment, And Psychomotor Retardation

NCBI Summary:This gene encodes a single-pass type I transmembrane protein, which is a subunit of the endoplasmic reticulum membrane protein complex (EMC). Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2012]
UniProt Code:Q8N766
NCBI GenInfo Identifier:74751081
NCBI Gene ID:23065
NCBI Accession:Q8N766.1
UniProt Secondary Accession:Q8N766,Q14700, Q5TG62, Q63HL0, Q63HL3, Q8NBH8, A8K6F3
UniProt Related Accession:Q8N766
Molecular Weight:112kDa
NCBI Full Name:ER membrane protein complex subunit 1
NCBI Synonym Full Names:ER membrane protein complex subunit 1
NCBI Official Symbol:EMC1  
NCBI Official Synonym Symbols:CAVIPMR; KIAA0090  
NCBI Protein Information:ER membrane protein complex subunit 1
UniProt Protein Name:ER membrane protein complex subunit 1
Protein Family:ER membrane protein complex
UniProt Gene Name:EMC1  
Anti-EMC1 Antibody (CAB10290)Western blot analysis of extracts of various cell lines, using EMC1 antibody (CAB10290) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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