Name: Anti-ELOVL5 Antibody (CAB16567)
Brand: Metabolism Antibodies 2
SKU: CAB16567
Availability: OutOfStock

Antibody Name:	Anti-ELOVL5 Antibody
Antibody SKU:	CAB16567
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 247-326 of human ELOVL5 (NP_001229757.1).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human
Positive Samples:	HepG2

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 247-326 of human ELOVL5 (NP_001229757.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	GVIW PCTF PLGW LYFQ IGYM ISLI ALFT NFYI QTYN KKGA SRRK DHLK DHQN GSMA AVNG HTNS FSPL ENNV KPRK LRKD
Gene ID:	60481
Uniprot:	Q9NYP7
Cellular Location:	Cell projection, Endoplasmic reticulum membrane, Multi-pass membrane protein, dendrite
Calculated MW:	9kDa/35kDa/38kDa
Observed MW:	37kDa

Synonyms:

ELOVL5, HELO1, SCA38, dJ483K16.1

Background:

This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene.

UniProt Protein Function:	ELOVL5: Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. Belongs to the ELO family.
UniProt Protein Details:	Protein type:EC 2.3.1.199; Lipid Metabolism - unsaturated fatty acid biosynthesis; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 6p12.1 Cellular Component: cell soma; dendrite; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane Molecular Function:fatty acid elongase activity; protein binding Biological Process: cellular lipid metabolic process; linoleic acid metabolic process; triacylglycerol biosynthetic process; unsaturated fatty acid biosynthetic process; unsaturated fatty acid metabolic process; very-long-chain fatty acid biosynthetic process Disease: Spinocerebellar Ataxia 38
NCBI Summary:	This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
UniProt Code:	Q9NYP7
NCBI GenInfo Identifier:	74753072
NCBI Gene ID:	60481
NCBI Accession:	Q9NYP7.1
UniProt Secondary Accession:	Q9NYP7,Q59EL3, Q5TGH5, Q6NXE7, Q7L2S5, Q8NCG4, Q9UI22 B4DZJ2, F6SH78,
UniProt Related Accession:	Q9NYP7
Molecular Weight:	9,580 Da
NCBI Full Name:	Elongation of very long chain fatty acids protein 5
NCBI Synonym Full Names:	ELOVL fatty acid elongase 5
NCBI Official Symbol:	ELOVL5
NCBI Official Synonym Symbols:	HELO1; SCA38; dJ483K16.1
NCBI Protein Information:	elongation of very long chain fatty acids protein 5
UniProt Protein Name:	Elongation of very long chain fatty acids protein 5
UniProt Synonym Protein Names:	3-keto acyl-CoA synthase ELOVL5
UniProt Gene Name:	ELOVL5
UniProt Entry Name:	ELOV5_HUMAN

Western blot analysis of extracts of HepG2 cells, using ELOVL5 antibody (CAB16567) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.

Antibodies

ELOVL5 Antibody (PACO04926)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)