Immunology Antibodies 2

Anti-ELMOD2 Antibody (CAB7859)

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SKU:
CAB7859
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology

Description

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Antibody Name:Anti-ELMOD2 Antibody
Antibody SKU:CAB7859
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 5-95 of human ELMOD2 (NP_714913.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:U-87MG, LO2
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 5-95 of human ELMOD2 (NP_714913.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LWEF FYGH FFRF WMKW LLRQ MTGK CELQ RIFD TYVG AQRT HRIE NSLT YSKN KVLQ KATH VVQS EVDK YVDD IMKE KNIN PEKD ASFK ICM
Gene ID:255520
Uniprot:Q8IZ81
Cellular Location:
Calculated MW:34kDa
Observed MW:37kDa
Synonyms:ELMOD2, 9830169G11Rik
Background:This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis.
UniProt Protein Function:ELMOD2: Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 4q31.1

Cellular Component: membrane

Molecular Function:GTPase activator activity

Biological Process: regulation of defense response to virus

Disease: Pulmonary Fibrosis, Idiopathic

NCBI Summary:This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by RefSeq, Sep 2010]
UniProt Code:Q8IZ81
NCBI GenInfo Identifier:74728441
NCBI Gene ID:255520
NCBI Accession:Q8IZ81.1
UniProt Secondary Accession:Q8IZ81,B2R712, D3DNZ0,
UniProt Related Accession:Q8IZ81
Molecular Weight:34,961 Da
NCBI Full Name:ELMO domain-containing protein 2
NCBI Synonym Full Names:ELMO domain containing 2
NCBI Official Symbol:ELMOD2  
NCBI Official Synonym Symbols:9830169G11Rik  
NCBI Protein Information:ELMO domain-containing protein 2
UniProt Protein Name:ELMO domain-containing protein 2
Protein Family:ELMO domain-containing protein
UniProt Gene Name:ELMOD2  
UniProt Entry Name:ELMD2_HUMAN
Anti-ELMOD2 Antibody (CAB7859)Western blot analysis of extracts of various cell lines, using ELMOD2 antibody (CAB7859) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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