Immunology Antibodies 1

Anti-ELMOD2 Antibody (CAB14205)

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SKU:
CAB14205
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology

Description

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Antibody Name:Anti-ELMOD2 Antibody
Antibody SKU:CAB14205
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-293 of human ELMOD2 (NP_714913.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse liver, Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-293 of human ELMOD2 (NP_714913.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QMTG KCEL QRIF DTYV GAQR THRI ENSL TYSK NKVL QKAT HVVQ SEVD KYVD DIMK EKNI NPEK DASF KICM KMCL LQIT GYKQ LYLD VESV RKRP YDSD NLQH EELL MKLW NLLM PTKK LNAR ISKQ WAEI GFQG DDPK TDFR GMGI LGLI NLVY FSEN YTSE AHQI LSRS NHPK LGYS YAIV GINL TEMA YSLL KSEA LKFH LYNL VPGI PTME HFHQ FYCY LVYE FDKF WFEE EPES IMYF NLYR EKFH EKIK GLLL DCNV ALTL KV
Gene ID:255520
Uniprot:Q8IZ81
Cellular Location:
Calculated MW:34kDa
Observed MW:35kDa
Synonyms:ELMOD2, 9830169G11Rik
Background:This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis.
UniProt Protein Function:ELMOD2: Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 4q31.1

Cellular Component: membrane

Molecular Function:GTPase activator activity

Biological Process: regulation of defense response to virus

Disease: Pulmonary Fibrosis, Idiopathic

NCBI Summary:This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by RefSeq, Sep 2010]
UniProt Code:Q8IZ81
NCBI GenInfo Identifier:74728441
NCBI Gene ID:255520
NCBI Accession:Q8IZ81.1
UniProt Secondary Accession:Q8IZ81,B2R712, D3DNZ0,
UniProt Related Accession:Q8IZ81
Molecular Weight:34,961 Da
NCBI Full Name:ELMO domain-containing protein 2
NCBI Synonym Full Names:ELMO domain containing 2
NCBI Official Symbol:ELMOD2  
NCBI Official Synonym Symbols:9830169G11Rik  
NCBI Protein Information:ELMO domain-containing protein 2
UniProt Protein Name:ELMO domain-containing protein 2
Protein Family:ELMO domain-containing protein
UniProt Gene Name:ELMOD2  
UniProt Entry Name:ELMD2_HUMAN
Anti-ELMOD2 Antibody (CAB14205)Western blot analysis of extracts of various cell lines, using ELMOD2 antibody (CAB14205) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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